Actively Recruiting
Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology
Led by University Hospital, Toulouse · Updated on 2026-05-07
1164
Participants Needed
21
Research Sites
299 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study seeks to validate the hypothesis that nulliparous pregnant women after Assisted Reproductive Technology (ART) are at high risk of preeclampsia and perinatal complications and represent a subgroup for which aspirin prophylaxis during pregnancy may be effective in the prevention of preterm preeclampsia and other perinatal adverse outcomes.
CONDITIONS
Official Title
Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Nulliparous women aged 18 years or more
- Pregnancy following assisted reproductive technology (ART), including IVF, ICSI, oocyte donation, or intrauterine insemination with sperm donor
- Singleton pregnancy
- Pregnancy between 9 and 14 weeks of gestation
- Affiliated to French Social Security Insurance or equivalent
- Provided written informed consent
You will not qualify if you...
- Major fetal abnormality
- Regular aspirin treatment (including for antiphospholipid syndrome)
- Allergies or contraindications to aspirin such as von Willebrand disease, peptic ulceration, or hemophilia
- Women legally protected by law
- Participation in another interventional study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 21 locations
1
CHU Angers
Angers, France
Actively Recruiting
2
CHU Bordeaux
Bordeaux, France
Actively Recruiting
3
CHU Clermont-Ferrand
Clermont-Ferrand, France
Actively Recruiting
4
CHU Dijon-Bourgogne
Dijon, France
Actively Recruiting
5
CHU Lille
Lille, France
Actively Recruiting
6
HCL - Groupement Hospitalier Est, Hôpital Femme Mère Enfant
Lyon, France
Actively Recruiting
7
AP-HM Hôpital de la Conception
Marseille, France
Actively Recruiting
8
AP-HM Hôpital Nord
Marseille, France
Actively Recruiting
9
CHU Montpellier
Montpellier, France
Actively Recruiting
10
CHRU Nancy
Nancy, France
Actively Recruiting
11
CHU Nantes
Nantes, France
Actively Recruiting
12
CHU Nîmes
Nîmes, France
Actively Recruiting
13
Groupe hospitalier St Joseph
Paris, France
Actively Recruiting
14
Hôpital Armand - Trousseau
Paris, France
Not Yet Recruiting
15
Hôpital Cochin
Paris, France
Actively Recruiting
16
CHI Poissy Saint Germain en Laye
Poissy, France
Actively Recruiting
17
CHU Poitiers
Poitiers, France
Not Yet Recruiting
18
CHU Rennes
Rennes, France
Actively Recruiting
19
CHU Saint Etienne, Hôpital Nord
Saint-Etienne, France
Actively Recruiting
20
CHU Strasbourg
Strasbourg, France
Actively Recruiting
21
CHU Toulouse
Toulouse, France
Actively Recruiting
Research Team
P
Paul GUERBY, MD
CONTACT
D
Delphine DUCHANOIS, Midwife
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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