Actively Recruiting
Assess the Risk of Cerebrovascular Disease
Led by Tang-Du Hospital · Updated on 2022-10-25
100
Participants Needed
1
Research Sites
320 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Intracranial artery stenosis is an important cause of ischemic stroke, but the degree of intracranial artery stenosis is not completely matched with the symptoms of ischemic stroke. Asymptomatic carotid stenosis (ACS) refers to does not appear related neurological symptoms of carotid stenosis and stroke or transient ischemic attack of carotid stenosis, did not happen cerebrovascular events such as stroke, but there have been a different degree of cognitive impairment, be badly in need of development of noninvasive imaging methods, objective evaluation of the ACS group cognitive impairment, and predict the ACS risk of ischemic stroke. Therefore, this topic proposed comprehensive cognitive assessment, CTA, double modal MRI techniques, clinical and biochemical indicator detection, mathematical modeling and statistical analysis techniques, assess the ACS group and normal person the cognitive ability, the difference of NVC and local perfusion, and follow-up ACS crowd of ischemic stroke and other cardiovascular events, discuss ACS and cognitive impairment, the correlation of NVC and local perfusion abnormalities, screening of radiographic predictor of ischemic stroke, and in the follow-up of ACS population in testing the sensitivity of the series of indicators and specific degrees.
CONDITIONS
Official Title
Assess the Risk of Cerebrovascular Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Mild stenosis group: CTA suggested carotid stenosis < 30%
- Moderate stenosis group: CTA suggested carotid stenosis of 30-69%
- Severe stenosis group: CTA indicated carotid stenosis ≥70%
You will not qualify if you...
- Dementia, MMSE score < 21
- Previous carotid stenosis related neurological symptoms or transient ischemic attack
- Other brain lesions such as trauma, tumor, inflammation, or major vessel complications like cerebral infarction or malacia
- Contraindications for MRI examination
- Recent use of psychoactive drugs or hormones
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wen Wang
Xi'an, China, 710038
Actively Recruiting
Research Team
W
Wen Wang, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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