Actively Recruiting
Assessing Ambulatory and Non-ambulatory Community Mobility in People With Lower Limb Amputation
Led by Virginia Commonwealth University · Updated on 2026-05-05
50
Participants Needed
1
Research Sites
66 weeks
Total Duration
On this page
Sponsors
V
Virginia Commonwealth University
Lead Sponsor
N
National Center for Advancing Translational Sciences (NCATS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Mobility is a fundamental aspect of daily life, enabling individuals to participate in social, occupational, and recreational activities. Community mobility, defined as movement in environments outside the home, is particularly important for quality-of-life. Following lower limb amputation (LLA), mobility limitations are common and persistent. With rehabilitation and prosthetic training, many regain the ability to ambulate but results vary as only 25 - 58% of patients regain ambulatory ability and less than half of those who become ambulatory achieve sufficient ability to walk in community settings. As a result, \~40% of people with LLA are ambulatory but also use wheeled mobility (e.g., wheelchair, scooter) for some or all of their community mobility tasks. To date, the complementary role of wheeled and ambulatory mobility in maximizing community mobility has been overlooked, with clinical research overwhelmingly focused on assessing and improving ambulatory ability despite its impracticality for many community settings.
CONDITIONS
Official Title
Assessing Ambulatory and Non-ambulatory Community Mobility in People With Lower Limb Amputation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Unilateral or bilateral major lower limb amputation (e.g., proximal to or through the ankle joint)
- More than 6 months since lower limb amputation
- Fitted with a prosthetic limb
- Use a wheelchair or scooter for mobility at least once per week
You will not qualify if you...
- Unstable heart condition including unstable angina, uncontrolled cardiac dysrhythmia, acute myocarditis, hypertension, and acute pericarditis
- Acute systemic infection
- Prisoner or institutionalized with restricted self-determined mobility
- Decisionally challenged with Modified Telephone Interview for Cognitive Status score 24 or less
- Undergoing active cancer treatment
- Participating in prosthetic rehabilitation
- Determined unsafe or inappropriate to participate by the principal investigator
- Inability to communicate verbally in English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Virginia Commonwealth University
Richmond, Virginia, United States, 23298
Actively Recruiting
Research Team
P
Paul Kline
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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