Actively Recruiting

Age: 18Years +
All Genders
NCT07472088

Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms

Led by University of Kansas Medical Center · Updated on 2026-05-07

36

Participants Needed

1

Research Sites

13 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patellofemoral joint (PFJ) pain is a common, often chronic, aching pain behind or around the kneecap, frequently called "runner's knee". It occurs when the kneecap does not glide smoothly over the thigh bone, often due to muscle weakness or overuse. It makes sitting for long periods, climbing stairs, or kneeling painful. Symptomatic knee osteoarthritis (OA) is a common, long-term condition where the protective cartilage in the knee joint wears away, causing the bones to rub together, leading to daily pain and stiffness. In simple terms, it is a "wear-and-tear" disease of the entire joint that makes walking, climbing stairs, or bending the knee difficult. The PFJ is where the patella (kneecap) meets the femoral trochlea (front part of the lower thigh bone) at the front of the knee. Patellar tracking refers to the movement of the patella that begins to engage in the distal femoral trochlear groove (smooth, U-shaped groove at the bottom of the thigh bone). By doing this study, we hope to advance clinical knowledge of the PTJ features in a more natural position by using weight-bearing computed tomography (WBCT) images while the leg is straight and slightly bent. Determining links between specific knee symptoms and the PTJ structure on WBCT images could enable providers to effectively target the underlying causes and to develop targeted treatments.

CONDITIONS

Official Title

Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Current knee pain classified as either patellofemoral joint pain (pain only in the front of the knee) or symptomatic knee osteoarthritis pain (pain in any area of the knee including the front)
Not Eligible

You will not qualify if you...

  • Both knees have had total knee replacement surgery
  • Pregnant
  • Unable to stand safely for 2 minutes even with support
  • Any condition that the investigator judges makes participation unsafe or inappropriate, such as inability to consent or safely stand on the WBCT platform

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

University of Kansas Medical Center

Kansas City, Kansas, United States, 66160

Actively Recruiting

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Research Team

J

Jessica Lee, PhD

CONTACT

Y

Yashaf Zaheer, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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