Actively Recruiting

Age: 13Years +
All Genders
NCT01099982

Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease

Led by University of Utah · Updated on 2025-07-15

300

Participants Needed

3

Research Sites

1008 weeks

Total Duration

On this page

Sponsors

U

University of Utah

Lead Sponsor

I

Intermountain Health Care, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Hypothesis: Tissue and serum samples collected from end-stage heart failure patients receiving left ventricular assist device implantation (LVAD) or heart transplantation will provide information regarding the basic science of heart disease. Tissue and serum samples collected from a limited numbers of "healthy controls" (donor grafts that were not utilized for heart transplantation) will serve as a comparator in research database projects. Design: This is a registry project; there are no investigational treatments, drug or procedures associated with participation in registry activities. This project is an organized functional data and tissue data gathering and storing (database) endeavor with specific focus on the functional, structural, and molecular aspects of heart failure. Data collection will not immediately influence the course of treatment for any patient.

CONDITIONS

Official Title

Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease

Who Can Participate

Age: 13Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 18 years old with heart failure undergoing LVAD implantation or heart transplantation
  • Children aged 13 to 18 years with heart failure whose body mass index can accommodate an LVAD
Not Eligible

You will not qualify if you...

  • Patient or their representative does not understand spoken English
  • Patient or their representative is unwilling to provide written consent for participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Intermountain Medical Center

Murray, Utah, United States, 84157

Actively Recruiting

2

University of Utah Health Sciences Center

Salt Lake City, Utah, United States, 84132

Actively Recruiting

3

VA Salt Lake City Health Care System

Salt Lake City, Utah, United States, 84148

Actively Recruiting

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Research Team

J

John Kirk

CONTACT

S

Stavros Drakos, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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