Actively Recruiting
By Assessing the Continuous Respiratory Physiological Changes Through Prone Position, Determine the Optimal Duration for Prone Position
Led by National Taiwan University Hospital · Updated on 2025-02-19
100
Participants Needed
1
Research Sites
327 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The prone position leads to a more homogeneous distribution of ventilation by inflation of collapsed alveoli and reduction in alveolar hyperinflation. By employing EIT, the study can obtain a thorough comprehension of the ongoing alterations in regional ventilation before and after adopting the prone position. It is also anticipated that there is an impact on inflammation biomarkers before and after the prone position. This assessment aids in determining the ideal duration for prone position therapy, encompassing the necessary hours and days in the prone position.
CONDITIONS
Official Title
By Assessing the Continuous Respiratory Physiological Changes Through Prone Position, Determine the Optimal Duration for Prone Position
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute respiratory distress syndrome
- Age over 18 years
- Serial arterial blood gas data showing PaO2/FiO2 less than 150
- Mechanical ventilator settings with FiO2 greater than 0.6 and PEEP greater than 5 cmH2O
You will not qualify if you...
- Presence of implantable electronic devices such as pacemakers
- Body mass index greater than 30
- Major thoracic or abdominal surgery
- Unstable spine or pelvis conditions
- Pregnancy in the second or third trimester
- Head trauma, elevated intracranial pressure, or elevated intraocular pressure
- Hemodynamic instability making prone ventilation unsafe
- Active seizures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Taiwan University Hospital
Taipei, Taiwan
Actively Recruiting
Research Team
T
Ting-Yu Liao, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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