Studying How Different Doses of Leucine-Enriched Super-Whey Protein Help Muscle Building in Men Aged 65 to 85

What this Trial Is About

Sarcopenia is the loss of skeletal muscle mass and function often seen in older adults, which can impact physical independence and metabolic health. Researchers are studying how different doses of a new leucine-enriched whey protein supplement, called super-whey, affect muscle building in older adults. This study aims to find the best dose to stimulate muscle protein synthesis, especially since muscle loss is linked to reduced response to protein and exercise in aging. Participants will receive three different low doses of the super-whey protein supplement 5 grams, 10 grams, and 20 grams. These doses will be given as single bolus servings in a randomized crossover manner, meaning each participant will try all doses in a random order. The doses are considered safe and similar to normal protein intake recommendations. The study will measure muscle protein synthesis both at rest and after acute exercise in older adults. During the study, participants will be monitored for muscle protein fractional synthetic rates at 3 and 6 hours after supplement intake. Blood samples will be taken over 7.5 hours to measure amino acid levels. Participants must be physically able to perform resistance exercise and will be assessed under close supervision by the research team. The study will help understand how different protein doses affect muscle building in older adults and will last until October 2026.

Assessing the Dose-response of Muscle Protein Synthesis to "Super-whey" in Older Adults