Actively Recruiting
Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts
Led by Sarah Nabia · Updated on 2026-02-25
672
Participants Needed
1
Research Sites
28 weeks
Total Duration
On this page
Sponsors
S
Sarah Nabia
Lead Sponsor
L
Liver Foundation, West Bengal
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn whether AI-enabled, nurse-led treatment planning can improve the quality of clinical reasoning and management compared with standard physician-led care in adult primary care patients (≥18 years) presenting with hypertension, diabetes mellitus, fever, breathlessness, or musculoskeletal pain in rural and semi-urban India. The main questions it aims to answer are: * Does a nurse + large language model (LLM) consultation achieve non-inferior clinical quality scores compared with a standard doctor consultation? * Is AI-assisted nurse-led care acceptable and satisfactory to patients in primary healthcare settings? Researchers will compare nurse + LLM-led consultations with physician-led standard-of-care consultations within the same participant to see if the AI-enabled nurse model delivers comparable or improved clinical reasoning and treatment planning. Participants will: * Receive two sequential consultations for the same visit (one with a nurse using an AI tool and one with a physician, order randomized). * Have both consultations audio recorded for blinded clinical quality assessment. * Complete a brief exit survey on communication, trust, and satisfaction after the AI-assisted nurse consultation.
CONDITIONS
Official Title
Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 2 years or older
- Presenting to participating primary care facilities in study sites
- Having at least one of the following: known hypertension, known diabetes mellitus or lab evidence (HbA1c 6.5%, fasting blood glucose 126 mg/dL, or post-prandial glucose 200 mg/dL), fever as chief complaint, breathlessness as chief complaint without fever, or musculoskeletal pain as chief complaint without fever
- Able and willing to provide written informed consent
- Willing to participate in two sequential consultations and complete an exit survey
You will not qualify if you...
- Unable to provide informed consent due to cognitive impairment (e.g., dementia or intellectual disability)
- Medically unstable or requiring immediate emergency referral
- Prior participation in the study during an earlier visit
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Liver Foundation
Kolkata, West Bengal, India
Actively Recruiting
Research Team
S
Sarah Nabia, MA, MPH, MBA
CONTACT
A
Anup Agarwal, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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