Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06949423

Assessing the Impact of dTMS on Neural Targets Associated With Alcohol Use Disorder

Led by Stanford University · Updated on 2026-05-11

100

Participants Needed

1

Research Sites

193 weeks

Total Duration

On this page

Sponsors

S

Stanford University

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the efficacy of deep transcranial magnetic stimulation as a treatment for Veterans with Alcohol Use Disorder (AUD) to decrease the exceedingly high rate of relapse associated with this condition.

CONDITIONS

Official Title

Assessing the Impact of dTMS on Neural Targets Associated With Alcohol Use Disorder

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-75
  • Current DSM-5 diagnosis of moderate to severe Alcohol Use Disorder with at least 4 diagnostic symptoms
  • Ability to obtain a Motor Threshold during screening
  • Stable condition and environment to attend scheduled clinic visits
  • Able to read, understand, and voluntarily sign informed consent
  • Stable medication regimen for comorbid symptoms during treatment phase
  • Fluent in English
Not Eligible

You will not qualify if you...

  • Contraindications for TMS or MRI such as pacemaker, cochlear implant, deep brain stimulation, metal near treatment coil, claustrophobia, pregnancy, or breastfeeding
  • Medical or neurological conditions interfering with assessments or participation
  • Unable to safely stop medications that increase seizure risk at least two weeks before treatment
  • Current substance abuse except caffeine or nicotine
  • Presence of mass lesion, cerebral infarct, active CNS disease, alcohol-related seizure, or seizure disorder
  • Recent suicide attempt within 30 days or current suicidal plan or intent
  • Severe vision, hearing, or hand movement impairments
  • Traumatic brain injury with loss of consciousness over 10 minutes
  • Use of benzodiazepines, neuroleptics, or medications altering seizure threshold
  • Acute or unstable chronic illness
  • Current or past bipolar disorder or psychosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA Palo Alto Health Care System

Palo Alto, California, United States, 94304

Actively Recruiting

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Research Team

S

Samantha J Ward, BS

CONTACT

E

Eileen G Fischer, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Assessing the Impact of dTMS on Neural Targets Associated With Alcohol Use Disorder | DecenTrialz