Improving MRI Techniques to Measure Body Tissues in Healthy Adults 18 to 100 Years Old

What this Trial Is About

Researchers are studying how to improve magnetic resonance imaging MRI techniques to better measure and understand the anatomy and physiology of healthy human tissues. The study focuses on developing and optimizing new quantitative MRI methods to enhance the reliability and reproducibility of MRI measurements across different scanners and over time. This research aims to identify MRI metrics that could serve as useful biomarkers in medical practice. Participants in this observational study will undergo at least one MRI scan targeting areas such as the brain, liver, prostate, breast, or other body parts. The MRI process involves lying still inside a scanner, with noise protection and communication options provided. Some participants may perform tasks on a computer during the scan. Participants can have up to five scans within three months and may have as many as 30 visits per year, remaining in the study for up to two years. During participation, individuals will be screened and receive a neurological physical exam along with questionnaires. Researchers will assess the reproducibility of MRI metrics and evaluate factors affecting their variability. Safety measures include ensuring participants can tolerate the scan environment, and all data collection is completed by the study end. The study involves ongoing assessments over the participation period, lasting up to two years.

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects