Actively Recruiting
Assessing Neurocognition After Cerebrovascular Intervention
Led by University of California, San Diego · Updated on 2025-02-06
20
Participants Needed
1
Research Sites
228 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Decreased blood flow to the brain can cause decreased cognitive function. Carotid disease can result in decreased blood flow to the brain. The investigators seek to assess this relationship prospectively through performing a battery of neurocognitive assessments, collection of serum markers of inflammation, and through neuroimaging at two points before intervention (2 months and 1 month before stenting) and at two points after intervention (1 month and 2 months after intervention). The goal is to provide prospective evidence to identify the extent to which carotid stenosis and hypoperfusion of the brain results in diminished neurocognitive performance, and see if serum biomarkers before and after stenting correlate with these findings.
CONDITIONS
Official Title
Assessing Neurocognition After Cerebrovascular Intervention
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients older than 18 years of age
- Ultrasound evidence of carotid stenosis with either 50% or greater symptomatic stenosis or 70% or greater asymptomatic stenosis
You will not qualify if you...
- Patients younger than 18 years of age
- Incompatibility for MRI scanning
- Needing carotid stenting for reasons other than long-standing stenosis
- Emergency carotid stenting for acute symptoms like crescendo transient ischemic attacks or intolerance of normal blood pressure
- Lack of capacity to understand the study risks and benefits or inability to consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UCSD Medical Center
San Diego, California, United States, 92103
Actively Recruiting
Research Team
A
Alexander Khalessi, MD
CONTACT
A
ARVIN WALI, BA, MAS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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