Actively Recruiting
Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes
Led by Pennington Biomedical Research Center · Updated on 2025-07-31
48
Participants Needed
1
Research Sites
166 weeks
Total Duration
On this page
Sponsors
P
Pennington Biomedical Research Center
Lead Sponsor
P
Prachi Singh
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of this study is to assess the effects of Hass Avocados on glycemic control. The investigators hypothesize that Hass Avocado consumption will reduce fasting blood sugar compared to an isocaloric amount of other fruit during controlled feeding.
CONDITIONS
Official Title
Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant reported diagnosis of Type 2 diabetes
- HbA1c between 5.7% and 11% inclusive and/or fasting blood glucose of 25 100 mg/dL
- BMI 27-50 kg/m2 inclusive
- Age 18 to 65 years inclusive
- On stable medication regimen for at least 3 months (brief medication courses allowed)
- Willing to follow all study protocol requirements including blood draws
- Under care of a physician managing diabetes
- Willing to allow release of trial information to their treating physician
You will not qualify if you...
- Not willing or unable to consume study foods including avocados
- Participation in a weight control program within past 3 months or weight loss 25 5 kg in past 3 months
- Taking prescription or OTC weight loss medications within last 4 weeks
- History of weight loss surgery in last 5 years
- History of major surgery within last 3 months
- Type 1 diabetes, insulin-dependent type 2 diabetes, or thiazolidinedione use
- Renal insufficiency with potassium > 5.5 mmol/L or creatinine > 2.5 mg/dL
- Bilirubin > 3 mg/dL or albumin < 3 g/dL
- ALT > 3 times upper limit of normal
- More than 1 severe hypoglycemic event in past 12 months without physician clearance
- On high dose diuretics (furosemide 40mg or higher)
- Unstable heart disease or implanted cardiac defibrillator
- Blood pressure 25180/100 mm Hg (retest allowed within 1 week)
- Untreated or recently changed thyroid disease treatment
- Uncontrolled gastrointestinal disorders
- Current or recent cancer treatment or history within 3 years (except resected non-melanoma skin cancer)
- Dementia, psychiatric illness, or substance abuse affecting adherence
- Women who are pregnant, lactating, trying to become pregnant, or unwilling to use birth control
- Consuming >14 alcoholic drinks per week and unwilling to stop during study
- Participation in another clinical trial within 30 days
- Any condition deemed inadvisable for participation by study physician
AI-Screening
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Trial Site Locations
Total: 1 location
1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808
Actively Recruiting
Research Team
J
John W Apolzan, PhD
CONTACT
R
Rob Leonard
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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