Actively Recruiting

Age: 21Years +
All Genders
Healthy Volunteers
NCT07222293

Assessment of AI Program 'DRISTi' as a Screening Tool

Led by Artelus AI · Updated on 2025-12-09

900

Participants Needed

2

Research Sites

14 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A study will be conducted to demonstrate that DRISTi will correctly diagnose Diabetic Retinopathy (e.g., mtmDR, PDR, DME) in eyes of patients with diabetes. Participants who have been diagnosed with diabetes mellitus and meet the other inclusion/exclusion criteria will be invited to participate and will consent to have ophthalmic images taken. These images will be analyzed by DRISTi AI software and evaluated by an ophthalmic reading center. The results will be compared, and a statistical analysis will be completed to ensure statistical significance in the outcomes thus proving DRISTi is an effective DR diagnosis tool.

CONDITIONS

Official Title

Assessment of AI Program 'DRISTi' as a Screening Tool

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to sign and date the informed consent form
  • Willingness to comply with all study procedures and availability for the duration of the study
  • Age 21 years or older
  • Diagnosed with diabetes mellitus based on criteria from WHO or ADA, including:
    • Hemoglobin A1c (HbA1c) 6.5% or higher
    • Fasting Plasma Glucose (FPG) 126 mg/dL or higher
    • Symptoms of high blood sugar with random plasma glucose 200 mg/dL or higher
Not Eligible

You will not qualify if you...

  • Persistent visual impairment in one or both eyes
  • History of macular edema or retinal vascular (vein or artery) occlusion
  • History of ocular injections, laser treatment of the retina, or intraocular surgery other than uncomplicated cataract surgery
  • Contraindication for fundus photography, such as light sensitivity
  • Contraindications for mydriatic medications or unwilling/unable to dilate
  • Currently enrolled in an interventional study for the same condition
  • Any condition or situation that may confound study results or interfere with participation
  • Adults unable to consent due to impaired decision-making
  • Individuals who are not adults (infants, children, teenagers)
  • Pregnant women
  • Prisoners

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

New Century Ophthalmology - Oxford

Oxford, North Carolina, United States, 27565

Actively Recruiting

2

New Century Ophthalmology - Raleigh

Raleigh, North Carolina, United States, 27617

Actively Recruiting

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Research Team

J

Jeanne Champion, Primary Site Coordinator Oxford

CONTACT

A

Adriana Valencia, Site Coordinator Raleigh

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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