Actively Recruiting

FEMALE
Healthy Volunteers
NCT05305092

Assessment of Brain Cognitive Impairment in Breast Cancer

Led by Tang-Du Hospital · Updated on 2022-07-13

90

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

Sponsors

T

Tang-Du Hospital

Lead Sponsor

X

Xi'an Jiaotong University

Collaborating Sponsor

AI-Summary

What this Trial Is About

To explore the cognitive impairment caused by chemotherapy and endocrine therapy in premenopausal breast cancer patients and to find biomarkers with early predictive effect on this cognitive impairment by using multimodal integrated PET/MRI technology combined with psychobehavioral technology.

CONDITIONS

Official Title

Assessment of Brain Cognitive Impairment in Breast Cancer

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with primary stage I-II breast cancer.
  • Premenopausal women based on National Comprehensive Cancer Network Breast Cancer Guidelines.
  • No treatment other than surgery has started (if neoadjuvant chemotherapy is needed, enrollment before chemotherapy starts).
  • Eastern Cooperative Oncology Group score of 0-1 points.
  • Ability to understand and complete various scales.
  • Right-handed.
  • Female subjects of childbearing potential must use medically-approved contraception during the study.
  • Signed informed consent and voluntary participation in the clinical observation.
Not Eligible

You will not qualify if you...

  • Central nervous system disease, history of malignancy, chronic loss of consciousness, head trauma, or any disease affecting cognitive function.
  • Current or former epilepsy, dementia, or learning disabilities.
  • Past psychiatric history.
  • Past history of malignancy.
  • MRI contraindications such as pacemakers, defibrillators, hearing aids, insulin pumps, drug dose control devices, or other metal implants.
  • Severe hyperthermia.
  • Claustrophobia.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tangdu Hospital

Xi'an, Shaanxi, China, 710038

Actively Recruiting

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Research Team

M

Menghui Yuan, phd

CONTACT

L

Lijun Bai, phd

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Assessment of Brain Cognitive Impairment in Breast Cancer | DecenTrialz