Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06682286

Assessment of Breathing Pattern During NIV

Led by Fisher and Paykel Healthcare · Updated on 2025-05-11

40

Participants Needed

1

Research Sites

31 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

COPD and OHS are respiratory conditions that disrupt normal breathing. Positive airway pressure, specifically Non-Invasive Ventilation (NIV), has been shown to improve breathing and reduce symptoms in patients with these conditions. Regular use of NIV can lead to better symptom management, improved quality of life, and reduced use of healthcare resources. The type of mask used for breathing support can greatly affect a patient's comfort and willingness to use it. For conditions like Obstructive Sleep Apnea (OSA), which is a physical blockage of the airway caused by the relaxation of the muscles of the throat, nasal masks are often used because they are comfortable and work well. But for breathing support in the hospital, full face masks are typically used because patients are having significant trouble breathing and tend to breathe through their mouth. However, it's important to note that we don't yet fully understand the best way to provide breathing support for long-term NIV users, like COPD and OHS patients. The understanding of breathing route is currently only established for OSA. However, conditions like COPD affect the lungs and the overall system used for breathing, which is different from the throat blockage seen in OSA. So, the assumptions we make based on conditions like OSA may not apply to these other conditions. More research is needed to understand this better.

CONDITIONS

Official Title

Assessment of Breathing Pattern During NIV

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Prescribed nocturnal Non-Invasive Ventilation (NIV) for COPD or Obesity Hypoventilation Syndrome (OHS)
  • Able to complete an overnight sleep study
  • Comfortable to sleep on a standard double bed
  • Capacity to complete informed consent
Not Eligible

You will not qualify if you...

  • Uncontrolled sleep apnea with Apnea-hypopnea index (AHI) over 15 events/hour off personal NIV device data
  • Prescribed inspiratory positive airway pressure (IPAP) above 25 cmH2O
  • Self-reported pregnancy
  • Allergy to adhesive of the sensors
  • Self-reported cold or flu symptoms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fisher and Paykel Healthcare Sleep Laboratory

Auckland, New Zealand, 2013

Actively Recruiting

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Research Team

V

Valeria Mereacre, PhD Physiology

CONTACT

J

Jessica Fogarin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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