Assessment of Complication Risk Factors in a French National Cohort of Asplenic Patients

What this Trial Is About

This research aims to understand the risks of complications in patients without a spleen asplenic patients in France. These patients may have lost spleen function due to surgery for trauma, cancer, autoimmune disease, or diagnostic reasons, or due to treatments like radiotherapy or splenic artery embolism. The study focuses on evaluating the risks of infections, cancer, and blood clot diseases in this group, as these complications are not well understood. The study observes patients with asplenia caused by splenectomy, splenic artery embolization, or radiotherapy. It plans a long-term follow-up to assess how splenic function and immunity change over time among different patient groups. New tools to assess residual spleen function will be used to improve patient management and better estimate the rates of infectious and non-infectious complications. Participants will be followed prospectively with evaluations over a period of three years. Researchers will monitor and assess complications and risk factors during this time. The main outcome measured is the assessment of complication risk factors related to asplenia. This observational study does not involve treatments but focuses on detailed follow-up of health outcomes and splenic function.

Assessment of Complication Risk Factors in a French National Cohort of Asplenic Patients