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ID07456020

Comparing Two Behavioral Tests to Assess Consciousness After Severe Brain Injury Using CRS-R and SECONDs in Neurological Rehabilitation

Led by BDH-Klinik Hessisch Oldendorf · Updated on 2026-03-11

110

Participants Needed

1

Research Sites

17 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating diagnostic methods to better assess consciousness levels in patients with severe brain injury. This study focuses on improving the accuracy and feasibility of evaluating consciousness disorders, such as coma, Unresponsive Wakefulness Syndrome UWS, and Minimally Conscious State MCS. The study compares two behavioral assessment tools the widely used Coma Recovery Scale-Revised CRS-R and a newer, shorter tool called the Simplified Evaluation of CONsciousness Disorders SECONDs. Participants will undergo structured behavioral assessments using both the SECONDs and CRS-R tools during a neurological rehabilitation phase. The study will analyze the diagnostic consistency and clinical relevance of SECONDs compared to CRS-R, aiming to confirm whether SECONDs offers a reliable and quicker alternative for routine clinical use. The study also includes a follow-up 12 months later to evaluate long-term functional outcomes based on initial SECONDs assessments. During the study, patients will be assessed shortly after admission to rehabilitation 6-8 days using both tools. Follow-up information will be collected via structured telephone interviews with relatives or legal representatives to monitor patients functional status one year later. Researchers will measure agreement between SECONDs and CRS-R scores, diagnostic stability, prognostic value for long-term outcomes, and the practical feasibility of SECONDs in clinical settings.

CONDITIONS

Brief Title

Assessment of Consciousness With CRS-R and SECONDs

Research Team

M

Melanie Boltzmann, PhD

S

Simone B. Jenner

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