Actively Recruiting

Phase Not Applicable
Age: 14Years - 70Years
All Genders
NCT04578769

Assessment of Different Modified POEM for Achalasia

Led by Peking Union Medical College Hospital · Updated on 2025-12-10

52

Participants Needed

1

Research Sites

299 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aims of this study is to compare the efficacy and safety of conventional myotomy (circular myotomy) and modified myotomy (full-thickness myotomy) in the treatment of achalasia patients.

CONDITIONS

Official Title

Assessment of Different Modified POEM for Achalasia

Who Can Participate

Age: 14Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed as achalasia type I or II according to Chicago Classification Version 4.0 with an Eckardt score greater than 3
  • Age between 14 and 70 years
  • Able to provide written consent
Not Eligible

You will not qualify if you...

  • Previous surgical treatments
  • Contraindication to general anesthesia
  • Previous surgery of the mediastinum, stomach, or esophagus
  • Pregnant or lactating female
  • Type III achalasia
  • Current alcohol or drug addiction, mental retardation, or severe congenital or acquired coagulopathy (INR >1.6)
  • Hepatic cirrhosis with or without portal hypertension, eosinophilic esophagitis, or confirmed Barrett's esophagus
  • Esophageal diverticula or hiatal hernia or other conditions deemed unsuitable for POEM by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Gastroenterology, Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

T

Tao Guo, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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