Actively Recruiting
Assessment of Eloquent Function in Brain Tumor Patients
Led by University of Nebraska · Updated on 2026-01-13
75
Participants Needed
1
Research Sites
826 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Purpose of the study: AIM 1: Prospectively collect pre-operative \[functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)\] and intra-operative mapping data in patients with intra-axial brain tumors to assess how well each modality predicts the location of eloquent brain function. In addition, each modality will be compared with the other. AIM 2: Assess reorganization of eloquent brain function and plasticity in patients with intra-axial brain tumors. This will be accomplished by prospectively collecting post-operative mapping studies and neuropsychological tests to compare them to prior mapping studies as stated above.
CONDITIONS
Official Title
Assessment of Eloquent Function in Brain Tumor Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 19 years and older
- Brain tumor in or near eloquent brain regions that is appropriate for attempted resection
- Appropriate body habitus and mental status/capacity to participate with non-invasive or invasive mapping
- Benign or malignant intra-axial brain tumor
- Primary or metastatic intra-axial brain tumor
You will not qualify if you...
- Any contraindication to MRI (i.e. implanted devices)
- Inappropriate body habitus or mental status/capacity to participate with non-invasive or invasive mapping in a safe and reliable manner
- Declining to participate
- Lacks capacity to understand the study or consent for themselves
- Neurologic status which precludes testing (poor function- not testable)
- Positive pregnancy test
- End stage renal disease or severe renal dysfunction
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198
Actively Recruiting
Research Team
D
Dulce Maroni, PhD
CONTACT
K
Katie Maire, MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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