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ID04921020

Assessment of Eyelid Topology and Kinetics Using Deep Learning in Eyelid Diseases

Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2021-06-10

500

Participants Needed

1

Research Sites

52 weeks

Total Duration

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AI-Summary

What this Trial Is About

Researchers are evaluating eyelid conditions using deep learning methods to automatically analyze eyelid shape and blinking patterns. The study aims to measure features like margin reflex distance, eyelid contour, corneal exposure area, and blinking frequency, velocity, and duration. It also seeks to predict different types of levator muscle function based on blinking characteristics. This observational research involves people with various eyelid diseases as well as normal volunteers. Participants include normal individuals and patients with blepharoptosis, blepharospasm, dry eye disease, or Graves' disease. Facial photographs and blinking videos are collected to capture eyelid topology and kinetics. These images and videos are then analyzed using deep learning techniques to extract one-dimensional and two-dimensional eyelid parameters and to classify levator muscle function subtypes. Throughout the study, which lasts up to 5 years, researchers will monitor eyelid features and blinking behavior using the collected visual data. The primary outcomes include detailed measures of eyelid shape and function assessed continuously during the study period. This long-term observation will help improve understanding of eyelid diseases and develop new methods for their assessment.

CONDITIONS

Brief Title

Assessment of Eyelid Topology and Kinetics Based on Deep Learning Method

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Normal volunteers without eyelid diseases
  • Patients with blepharoptosis
  • Patients with blepharospasm
  • Patients with dry eye disease
  • Patients with Graves' disease
Not Eligible

You will not qualify if you...

  • Variable ptosis such as myasthenia gravis
  • Entropion
  • Ectropion
  • Enophthalmos
  • Exophthalmos
  • Strabismus
  • Abnormalities of pupil

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Through study completion, up to 5 years

Participants undergo facial photography and blinking video recordings to assess eyelid topology and kinetics.

1 to 2 visits depending on participant group

Long-term Monitoring

Duration - Up to 5 years

Participants are monitored over time to observe changes in eyelid parameters and levator function.

Periodic visits as scheduled during the study period

Trial Site Locations

Total: 1 location

1

Juan Ye

Hangzhou, Zhejiang, China, 310000

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Research Team

J

Juan Ye

L

Lixia Lou

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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