Actively Recruiting
Assessment of Eyelid Topology and Kinetics Using Deep Learning in Eyelid Diseases
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2021-06-10
500
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating eyelid conditions using deep learning methods to automatically analyze eyelid shape and blinking patterns. The study aims to measure features like margin reflex distance, eyelid contour, corneal exposure area, and blinking frequency, velocity, and duration. It also seeks to predict different types of levator muscle function based on blinking characteristics. This observational research involves people with various eyelid diseases as well as normal volunteers. Participants include normal individuals and patients with blepharoptosis, blepharospasm, dry eye disease, or Graves' disease. Facial photographs and blinking videos are collected to capture eyelid topology and kinetics. These images and videos are then analyzed using deep learning techniques to extract one-dimensional and two-dimensional eyelid parameters and to classify levator muscle function subtypes. Throughout the study, which lasts up to 5 years, researchers will monitor eyelid features and blinking behavior using the collected visual data. The primary outcomes include detailed measures of eyelid shape and function assessed continuously during the study period. This long-term observation will help improve understanding of eyelid diseases and develop new methods for their assessment.
CONDITIONS
Brief Title
Assessment of Eyelid Topology and Kinetics Based on Deep Learning Method
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Normal volunteers without eyelid diseases
- Patients with blepharoptosis
- Patients with blepharospasm
- Patients with dry eye disease
- Patients with Graves' disease
You will not qualify if you...
- Variable ptosis such as myasthenia gravis
- Entropion
- Ectropion
- Enophthalmos
- Exophthalmos
- Strabismus
- Abnormalities of pupil
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Through study completion, up to 5 years
Participants undergo facial photography and blinking video recordings to assess eyelid topology and kinetics.
1 to 2 visits depending on participant group
Duration - Up to 5 years
Participants are monitored over time to observe changes in eyelid parameters and levator function.
Periodic visits as scheduled during the study period
Trial Site Locations
Total: 1 location
1
Juan Ye
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
J
Juan Ye
L
Lixia Lou
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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