Actively Recruiting
Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors
Led by M.D. Anderson Cancer Center · Updated on 2026-04-21
300
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand the symptoms and changes experienced by patients treated for sinonasal, nasopharyngeal, and skull base tumors. It focuses on survivors of both benign and malignant tumors in these areas, estimating how often and how severe adverse and functional outcomes are. The study also looks at health-promoting behaviors during survivorship and seeks to identify factors that affect these outcomes. A database will be created to collect demographic, clinical, recurrence, survival, functional, and patient-reported outcome information for these patients. Participants will undergo standard care assessments that include tests related to hormone levels, hearing, eye health, dental and jaw function, and speech and swallowing abilities. These evaluations are part of the behavioral interventions used to monitor patients’ function throughout the study. During the study, researchers will assess patients using the MD Anderson Symptom Inventory Head and Neck Module to measure symptoms over about one year. Patients will be monitored for their functional impairments and symptom burden, and data will be collected continuously through study completion. The total duration and detailed monitoring schedule support a thorough understanding of survivorship outcomes.
CONDITIONS
Brief Title
Assessment of Functional and Symptom Outcomes for Survivors of Paranasal Sinus, Nasopharyngeal and Skull Base Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Previously untreated patients with or suspected to have sinonasal or nasopharyngeal malignancy diagnosis based on pathology reports
- Age 18 years or older
- Plan to receive the majority of treatment at MD Anderson Cancer Center including surgery and radiotherapy
- Ability to understand and willingness to sign written informed consent
You will not qualify if you...
- History of previous solid or liquid malignancies, except skin cancers treated with local therapy
- Existing neurocognitive impairment not caused by sinonasal or nasopharyngeal cancers or their treatment
- Previous treatment for sinonasal or nasopharyngeal carcinomas, other than biopsy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 year
Participants who undergo routine care are observed through assessments including pituitary hormone lab draws, audiogram hearing tests, eye exams, teeth and jaw exams, and speech and swallowing evaluations to estimate functional and symptom outcomes.
Multiple visits as part of standard care
Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
S
Shirley Su, MBBS
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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