Actively Recruiting
Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges
Led by Cairo University · Updated on 2026-04-14
32
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the effect of Allogenic bone graft mixed with Xenograft in ratio 1:1, on the radiographic and histomorphometric assessment versus Autologous bone graft mixed with Xenograft in ratio 1:1 in maxillary deficient ridges، In guided bone regeneration of deficient edentulous maxillary ridges, will the application of Xenograft mixed with Allograft (1:1) be as effective as Xenograft mixed with Autogenous graft (1:1) in terms of dimensional ridge changes and Quality of newly formed bone? Evaluation of the patient's general condition of the oral cavity, to make sure it complies with the criteria required to be enrolled in the study in terms of oral hygiene and pathological conditions. A full thickness flap will be elevated with two releasing incisions, decortication of the buccal aspect of the ridge, placing of grafting material which will be covered by collagen pericardium membranes, tacks placement at the labial side to fix the membrane in place, horizontal mattress sutures as well as single interrupted and continuous with resorbable sutures for closure. Intervention group: will be filled with mixture of Xenogenic graft and the Allogenic bone graft chips. Control group: will be filled with mixture of Xenogenic graft and Autogenous bone particulate harvested either the ramus. For both groups, All the subjects will be taking CBCT at pre surgical and 6 months post surgical. outcomes : Bucco-Palatal horizontal bone gain, Alveolar ridge height, Percentage of new vital bone formation and Percentage of residual bone graft 6 months post-surgical.
CONDITIONS
Official Title
Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 20 and 50 years
- Totally or partially edentulous maxillary ridges
- Insufficient bone for implant placement
- Residual alveolar width from 2 to 4 mm
- Minimum vertical bone height of 10 mm to nasal or sinus floor
- Healthy overall medical condition
- Adequate space between jaws for implant placement
You will not qualify if you...
- Presence of pathological lesions at the defect site
- Systemic diseases affecting bone metabolism, including uncontrolled diabetes
- Current or recent chemotherapy or radiotherapy
- Medical conditions that prevent surgery
- Use of medications that affect healing, such as corticosteroids or bisphosphonates
- Vertical bone deficiency
- Habits that could harm implant success, like alcoholism or para-functional habits
AI-Screening
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Trial Site Locations
Total: 1 location
1
Faculty of Dentistry Cairo University
Cairo, Egypt
Actively Recruiting
Research Team
M
Mohamed A. Abousetta
CONTACT
M
Mohamed M. Shaker
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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