Actively Recruiting

Phase Not Applicable
Age: 20Years - 50Years
All Genders
Healthy Volunteers
NCT07367464

Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges

Led by Cairo University · Updated on 2026-04-14

32

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effect of Allogenic bone graft mixed with Xenograft in ratio 1:1, on the radiographic and histomorphometric assessment versus Autologous bone graft mixed with Xenograft in ratio 1:1 in maxillary deficient ridges، In guided bone regeneration of deficient edentulous maxillary ridges, will the application of Xenograft mixed with Allograft (1:1) be as effective as Xenograft mixed with Autogenous graft (1:1) in terms of dimensional ridge changes and Quality of newly formed bone? Evaluation of the patient's general condition of the oral cavity, to make sure it complies with the criteria required to be enrolled in the study in terms of oral hygiene and pathological conditions. A full thickness flap will be elevated with two releasing incisions, decortication of the buccal aspect of the ridge, placing of grafting material which will be covered by collagen pericardium membranes, tacks placement at the labial side to fix the membrane in place, horizontal mattress sutures as well as single interrupted and continuous with resorbable sutures for closure. Intervention group: will be filled with mixture of Xenogenic graft and the Allogenic bone graft chips. Control group: will be filled with mixture of Xenogenic graft and Autogenous bone particulate harvested either the ramus. For both groups, All the subjects will be taking CBCT at pre surgical and 6 months post surgical. outcomes : Bucco-Palatal horizontal bone gain, Alveolar ridge height, Percentage of new vital bone formation and Percentage of residual bone graft 6 months post-surgical.

CONDITIONS

Official Title

Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges

Who Can Participate

Age: 20Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 20 and 50 years
  • Totally or partially edentulous maxillary ridges
  • Insufficient bone for implant placement
  • Residual alveolar width from 2 to 4 mm
  • Minimum vertical bone height of 10 mm to nasal or sinus floor
  • Healthy overall medical condition
  • Adequate space between jaws for implant placement
Not Eligible

You will not qualify if you...

  • Presence of pathological lesions at the defect site
  • Systemic diseases affecting bone metabolism, including uncontrolled diabetes
  • Current or recent chemotherapy or radiotherapy
  • Medical conditions that prevent surgery
  • Use of medications that affect healing, such as corticosteroids or bisphosphonates
  • Vertical bone deficiency
  • Habits that could harm implant success, like alcoholism or para-functional habits

AI-Screening

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Trial Site Locations

Total: 1 location

1

Faculty of Dentistry Cairo University

Cairo, Egypt

Actively Recruiting

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Research Team

M

Mohamed A. Abousetta

CONTACT

M

Mohamed M. Shaker

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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