Actively Recruiting
Assessment of Labial Plate Thickness After Immediate Implant Placement in Type II Extraction Sockets Using Two Different Xenografts in the Esthetic Zone: a Randomized Controlled Clinical Trial
Led by Basma Gamal Mohamed Ahmed · Updated on 2026-03-06
26
Participants Needed
1
Research Sites
20 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating changes in the labial bone plate after immediate implant placement in Type II extraction sockets using two different xenograft materials along with a de-epithelialized free gingival graft in the esthetic zone. This randomized clinical trial aims to compare the effects of these grafting materials on bone preservation and implant success. The study addresses concerns about bone changes following tooth extraction and immediate implant placement, focusing on maintaining bone and soft tissue structure in the front upper jaw area. Participants will undergo immediate implant placement after tooth extraction in the esthetic zone. They will be randomly assigned to one of two groups receiving defect grafting with either Medpark S1 xenograft or bio-Oss xenograft. Both groups will also receive a de-epithelialized free gingival graft during the procedure. The interventions involve placing the implant and grafting material in the extraction socket to support bone and tissue preservation. During the study, clinical evaluations and standardized radiographic assessments using CBCT scans will be conducted to measure changes in labial bone plate thickness and peri-implant bone stability. Implant success will be monitored over a follow-up period of six months. Researchers will assess outcomes such as bone thickness changes and peri-implant mucosal levels, ensuring participants' compliance and safety throughout the trial.
CONDITIONS
Brief Title
Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with one or more non-restorable teeth or remaining roots without signs of acute infection in the maxillary anterior region
- Type II extraction sockets
- Sufficient bone (>3 mm) apically and palatally to allow for proper implant positioning with sufficient primary stability (≥ 30 N cm)
- Good compliance
You will not qualify if you...
- Teeth with current acute periapical infection
- Medically compromised patients
- Heavy smokers (smoking of more than 10 cigarettes per day)
- Alcohol or drug abuse
- Patients undergoing chemotherapy and radiotherapy
- Poor oral hygiene
- Vulnerable groups (pregnant females and decision-impaired individuals)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single procedure with follow-up assessments over 6 months
Participants undergo immediate implant placement in Type II extraction sockets with defect grafting using either Medpark S1 or bio-Oss xenograft materials.
1 implant placement visit and multiple follow-up visits over 6 months
Duration - 6 months post-implant placement
Participants are monitored for labial bone plate thickness changes, peri-implant mucosal level, peri-implant bone stability, and implant success outcomes over a 6-month period after implant placement.
Several follow-up visits including standardized radiographic assessments
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Egypt
Actively Recruiting
Research Team
B
Basma Gamal, BDS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here