Actively Recruiting

Phase Not Applicable
Age: 30Years - 60Years
All Genders
NCT05715411

Assessment of Light Therapy in Insomnia Disorder

Led by University Hospital, Strasbourg, France · Updated on 2025-08-08

66

Participants Needed

1

Research Sites

87 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Sleep disorders represent a major public health issue and the leader in these disorders is insomnia with 10 to 15% of subjects in the general population reporting symptoms of insomnia with a daytime impact. In addition to being very common, insomnia leads to an increase in morbidity and mortality and weighs on healthcare systems worldwide. Despite this public health context, insomnia is underdiagnosed and rarely treated. Hypnotics have proven efficacy but with a risk of dependence and pharmacotolerance which appears within a few weeks. Cognitive behavioral therapy (CBT) has a good level of evidence and is now a benchmark treatment for the management of insomnia. Unfortunately, not all patients adhere to or respond to these procedures, which cannot be implemented for many of them either. There is therefore a need to identify other alternative therapeutic strategies, and we believe that exposure to light is a promising treatment. In this perspective, it seems interesting to assess the effect of the propensity to fall asleep with an exposure to light therapy in patients suffering from insomnia. In order to be in optimal ecological conditions, we want to use a portable light therapy device which allows easy, acceptable and ambulatory exposure. If the lighttherapy is confirmed in insomnia under ecological conditions, this would make it possible to propose a new non-drug treatment, easy to access and on a large scale

CONDITIONS

Official Title

Assessment of Light Therapy in Insomnia Disorder

Who Can Participate

Age: 30Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged 30 to 60 years
  • Diagnosed with insomnia disorder (ICSD-3) with sleep latency over 30 minutes at least 3 times a week
  • Able to understand the study and provide informed consent
  • Affiliated with a social health insurance scheme
  • Women of childbearing age must use effective contraception during the study
Not Eligible

You will not qualify if you...

  • Shift work in the year before enrollment
  • Travel across more than 2 time zones in the month before enrollment
  • Participation in another study exclusion period
  • Unable to receive informed information due to emergency or comprehension issues
  • Under judicial protection, guardianship, or curatorship
  • Pregnant or breastfeeding women of childbearing age
  • Use of drugs affecting sleep or melatonin measurement (corticosteroids, evening beta-blockers, exogenous melatonin)
  • Phase delay syndrome as defined by ICSD-3
  • Restless legs syndrome with IRLS score over 20
  • Other psychiatric or addictive disorders (screened by MINI interview)
  • Unstable medical conditions including chronic allergies, neurological, cardiovascular, respiratory, gastrointestinal, hematopoietic, visual, immune, kidney, urinary, endocrine, metabolic, infectious diseases, or epilepsy

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Hôpitaux Universitaires de Strasbourg

Strasbourg, France, 67000

Actively Recruiting

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Research Team

P

Patrice BOURGIN, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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