Actively Recruiting
Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data
Led by Technische Universität Dresden · Updated on 2025-08-20
200
Participants Needed
4
Research Sites
87 weeks
Total Duration
On this page
Sponsors
T
Technische Universität Dresden
Lead Sponsor
U
University Hospital Dresden
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to test the performance of neuronal networks trained on ultrasonic raw Data (=radiofrequency data) for the assessment of liver diseases in patients undergoing a clinical ultrasound examination. The general feasibility is currently evaluated in a retrospective cohort. The main questions the study aims to answer are: * Can a neuronal network trained on RF Data perform equally good as elastography in the assessment of diffuse liver diseases? * Can a neuronal network trained on RF Data perform better than a neuronal network trained on b-mode images in the assessment of diffuse liver diseases? * Can a neuronal network trained on RF Data distinguish focal pathologies in the liver from healthy tissue? To answer these questions participants with a clinically indicated fibroscan will undergo: * a clinical elastography in Case ob suspected diffuse liver disease * a reliable ground truth (if normal ultrasound is not sufficient e.g. contrast enhanced ultrasound, biopsy, MRI or CT) in case of focal liver diseases, depending on the standard routine of the participating center * a clinical ultrasound examination during which b-mode images and the corresponding RF-Data sets are captured
CONDITIONS
Official Title
Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for an ultrasound investigation by an independent physician
- Signed declaration of consent
You will not qualify if you...
- Minor liver interventions within the last 2 weeks (e.g., liver biopsy)
- Contrast-enhanced ultrasound performed less than one day ago
- Major liver interventions such as partial liver resection
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
University Hospital
Dresden, Germany, 01307
Actively Recruiting
2
Diakonissen Hospital Dresden
Dresden, Germany
Actively Recruiting
3
University Hospital Halle (Saale)
Halle, Germany
Actively Recruiting
4
University Hospital Leipzig
Leipzig, Germany
Actively Recruiting
Research Team
M
Moritz Herzog, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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