Study of Local Vitamin D3 and Corticision to Speed Up Orthodontic Canine Tooth Movement in Teens and Young Adults

What this Trial Is About

Researchers are evaluating the effect of locally administered vitamin D3 combined with a minimally invasive surgical technique called corticision on accelerating orthodontic canine retraction. This prospective clinical study aims to shorten orthodontic treatment time by speeding up tooth movement, which can reduce risks like gum inflammation and tooth decay. The study compares this combined approach to conventional orthodontic treatment in patients aged 13 to 20 years with specific dental conditions. Participants will be randomly assigned to one of two groups one group will receive local injections of vitamin D3 alongside corticision, a surgical method to stimulate bone remodeling, while the other group will undergo conventional treatment without these interventions. Vitamin D3 injections are given four times during the 12-week canine retraction period at set intervals. Tooth movement and bone density changes will be closely monitored during this time. Patients will be followed over three months with assessments including photographs, dental X-rays, study models, and cone beam computed tomography CBCT scans before and after treatment. Researchers will measure the rate and amount of canine movement as well as changes in alveolar bone density. Regular evaluations will ensure treatment progress and patient compliance. The primary outcome is the rate of canine retraction from baseline to three months, with secondary outcomes focusing on bone density changes in the treated area.

Assessment of the Locally Administrated Vitamin D3 and Corticision Efficacy on Orthodontic Canine Retraction