Actively Recruiting
Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients
Led by Emory University · Updated on 2026-03-09
180
Participants Needed
2
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of a 6-day low-dose oral methylprednisolone course, known as Medrol Dosepak, on pain, nausea, and opioid use in patients undergoing foot and ankle surgeries. The study also aims to monitor any complications and patient-reported outcomes following surgery. This research addresses the opioid epidemic by exploring ways to reduce opioid exposure through multimodal pain management, focusing on forefoot, ankle, and Achilles surgeries.
CONDITIONS
Brief Title
Assessment of Medrol Dosepak to Reduce Opioid Consumption in Foot and Ankle Surgical Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Emory Orthopedic patients undergoing foot and ankle surgery
You will not qualify if you...
- Concurrent or significant injuries to other bones or organs
- Local infections
- History of alcohol or medical abuse, including prior opioid abuse
- Smoking
- History of severe heart disease, renal failure, liver dysfunction, active peptic ulcer disease, diabetes, rheumatoid arthritis, neurological or psychiatric diseases that could influence pain perception
- Pre-existing immune suppression
- Those deemed possibly non-compliant by the study team
- Vulnerable populations including those unable to give consent, juveniles, pregnant women, prisoners, cognitively impaired, and non-English speaking individuals
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 days for Medrol Dosepak with pain and opioid use recorded for 7 days post surgery
Participants undergo foot and ankle surgery and receive either a 6-day low-dose oral Medrol Dosepak or standard pain management. They record pain, nausea, and opioid use starting the day of surgery and continuing for 7 days in a pain journal.
1 surgery day visit and daily self-reporting for 7 days post surgery
Duration - Up to 6 months
Participants attend a post-operative appointment approximately 2 weeks after surgery to review pain journals and evaluate for complications. Additional assessments occur at 1.5, 3, and 6 months to monitor complications and patient-reported outcomes.
1 visit around 2 weeks post surgery and additional visits for assessments at 1.5, 3, and 6 months
Trial Site Locations
Total: 2 locations
1
Emory Musculoskeletal Institute, Emory Orthopaedics & Spine Center
Atlanta, Georgia, United States, 30329
Actively Recruiting
2
Emory Sports Medicine Complex and Emory Orthopaedics and Spine Center
Johns Creek, Georgia, United States, 30022
Actively Recruiting
Research Team
J
Jason Bariteau, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here