Evaluating Bone and Mineral Disorders in Kidney Transplant Recipients and Hemodialysis Patients Compared to Osteoporosis Patients

What this Trial Is About

Researchers are evaluating bone health measurements in patients with chronic kidney disease and kidney transplant recipients to improve assessment of mineral and bone disorders related to kidney disease. This observational study compares bone mineral density, bone turnover markers, vertebral fracture assessment, and trabecular bone score among hemodialysis patients, kidney transplant recipients, and general population patients with osteopenia or osteoporosis. The goal is to enhance understanding of bone changes in these groups over time. Participants include three groups those undergoing hemodialysis for at least 12 months, kidney transplant recipients with a transplant performed at least 12 months prior, and men or postmenopausal women diagnosed with primary osteopenia or osteoporosis. Bone measurements and blood tests will be collected at the start and after one year, with or without treatment for mineral and bone disorders. The study does not intervene but observes and compares bone health parameters across groups. During the study, participants will undergo assessments including bone mineral density scans, bone turnover marker blood tests, vertebral fracture evaluations, and trabecular bone score measurements. Researchers will monitor changes in these parameters over 12 months to understand bone health differences and correlations in the study groups. Safety and treatment information will be recorded, and participants involvement will last about one year.

Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients