Actively Recruiting

Age: 18Years +
All Genders
ID07032766

Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures

Led by Albert Einstein College of Medicine · Updated on 2025-08-13

220

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

A

Albert Einstein College of Medicine

Lead Sponsor

J

Jacobi Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying the long-term effects of the serratus anterior plane block (SAPB) in adults with multiple unilateral anterolateral rib fractures who arrive at the emergency department within 24 hours of injury. The study aims to compare SAPB to standard opioid-based pain treatments to see if SAPB reduces complications like pneumonia, hospital stay length, discharge outcomes, and death. This observational study is conducted at a single urban trauma center. Patients eligible for the study will receive SAPB if a trained physician is available within 24 hours; otherwise, they will receive intravenous opioid analgesia. The SAPB involves ultrasound-guided injection of local anesthetic between muscles to target nerves for pain relief. Ultrasound imaging is used during the procedure to ensure correct needle placement and anesthetic spread. The study follows patients until discharge or up to 60 days. Participants will be monitored for outcomes such as hospital-acquired pneumonia, length of hospital and ICU stays, discharge disposition, and mortality within 90 days. Pain intensity is assessed before and after SAPB, and the need for additional analgesia is tracked within 24 hours. Data collection includes ultrasound images, clinical assessments, and patient consent. The study seeks to understand if SAPB improves recovery compared to standard pain management.

CONDITIONS

Brief Title

Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age being treated in the Emergency Department
  • Presenting within 24 hours of injury
  • Two or more unilateral, anterior or lateral rib fractures
  • Able to provide consent (patient or health care proxy)
  • Clinical team believes inpatient admission will be required at enrollment
Not Eligible

You will not qualify if you...

  • Patients in traumatic arrest or hemodynamic instability
  • Expected discharge from hospital within 24 hours
  • Prisoners
  • Pregnant patients
  • Children under 18 years old
  • Known or suspected allergy to anesthetic
  • Significant pain from other traumatic injury
  • Unable to provide consent or no healthcare proxy available
  • Bilateral or posterior rib fractures

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Duration - Up to 24 hours after initial analgesia administration

Participants receive either a serratus anterior plane block (SAPB) or standard intravenous opioid analgesia for pain management following unilateral rib fractures.

1 procedure visit (in-person) and assessments at 30 and 60 minutes post-procedure

Monitoring

Duration - Up to 90 days from emergency department arrival

Participants are monitored for morbidity and mortality outcomes including hospital acquired pneumonia, length of hospital stay, ICU stay, discharge disposition, and cause of death.

Follow-up assessments during hospital stay and up to 90 days post-admission

Trial Site Locations

Total: 1 location

1

Jacobi Medical Center

The Bronx, New York, United States, 10461

Actively Recruiting

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Research Team

A

Ariella Gartenberg, MD

M

Michelle Montenegro, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

Efficacy and safety of the serratus anterior plane block (SAP block) for pain management in patients with multiple rib fractures in the emergency department: a retrospective study.

Sossio Serra, Domenico Pietro Santonastaso, Giuseppe Romano...

https://pubmed.ncbi.nlm.nih.gov/39020130

Ultrasound-Guided Serratus Anterior Plane Block for Rib Fracture-Associated Pain Management in Emergency Department.

Subhankar Paul, Sanjeev Kumar Bhoi, Tej Prakash Sinha...

https://pubmed.ncbi.nlm.nih.gov/33304071

Ultrasound-Guided Serratus Anterior Plane Block (SAPB) Improves Pain Control in Patients With Rib Fractures.

Randy M Kring, David C Mackenzie, Christina N Wilson...

https://pubmed.ncbi.nlm.nih.gov/35106815