Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06923813

Assessment of Nutrient Absorption in Enterally Fed Post-intensive Care Unit Patients Using Bomb Calorimetry: do the Calories Stick

Led by Universitair Ziekenhuis Brussel · Updated on 2026-05-01

20

Participants Needed

2

Research Sites

116 weeks

Total Duration

On this page

Sponsors

U

Universitair Ziekenhuis Brussel

Lead Sponsor

S

Société des Produits Nestlé (SPN)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study focuses on understanding how well patients who have recovered from an ICU stay absorb nutrients when receiving enteral (tube) feeding. Proper nutrition is crucial for recovery, but we don't fully understand how efficiently enteral feeding works in ICU survivors. The study will use advanced techniques like bomb calorimetry to measure the energy content of stool, and indirect calorimetry to measure patients' resting energy expenditure (REE). This will help assess the effectiveness of enteral feeding in these patients, providing valuable information about their metabolic needs and nutritional status. The study will also look into the environmental impact of enteral feeding, particularly food waste. By understanding how much of the nutrition is absorbed versus excreted, the study hopes to suggest more sustainable feeding practices and reduce unnecessary waste in hospitals. Key Goals: * Primary Goal: Measure how much energy from enteral feeding is absorbed by patients post-ICU by analyzing their stool and energy expenditure. * Secondary Goal: Assess how enteral feeding can be made more sustainable, with less waste generated from unused nutritional products. This research will help improve nutritional care for ICU patients, enhance recovery, and potentially lead to more environmentally friendly healthcare practices.

CONDITIONS

Official Title

Assessment of Nutrient Absorption in Enterally Fed Post-intensive Care Unit Patients Using Bomb Calorimetry: do the Calories Stick

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age of 18 years or older
  • Minimum ICU stay of 7 days
  • Fully dependent on enteral feeding (nasogastric or PEG-tube)
  • Ability of the patient or representative to understand and sign written informed consent in Dutch, French, or English
Not Eligible

You will not qualify if you...

  • Known inflammatory bowel disease
  • Known malabsorptive gastrointestinal disease
  • History of small bowel resection
  • Use of serotoninergic or sympathomimetic medications such as setrone, triptans, antidepressants, methylphenidate, monoamine oxidase inhibitors, or tramadol

AI-Screening

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Trial Site Locations

Total: 2 locations

1

UZ Brussel

Brussels, Belgium

Not Yet Recruiting

2

UZ Brussel

Jette, Belgium, 1090

Actively Recruiting

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Research Team

E

Elisabeth De Waele

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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