Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
ID07321977

Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic Volunteers

Led by Institut de Myologie, France · Updated on 2026-05-19

30

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating markerless gait analysis in adults with neuromuscular diseases or in asymptomatic volunteers. This study aims to improve monitoring of walking biomechanics, which current gait tests may not fully capture, especially given the slow progression of symptoms in these conditions. The study focuses on quantifying gait parameters using a portable digital device to allow for easier and effective assessment without complex equipment. Participants will walk with shoes in a gait analysis room while wearing VICON markers on their body. Simultaneously, two smartphones will record video to compare the traditional marker-based gait analysis with the markerless system using motion analysis software. All participants receive the same intervention involving walking and simultaneous recording for comparison. During the study, participants will be evaluated on how well the markerless system correlates with the VICON system on the first day. Researchers will collect data on walking biomechanics through the two methods. Participants must be able to walk and stand independently for certain periods and will be monitored for their ability to perform specific physical tasks. The study includes adults aged 18 to 65, both with neuromuscular diseases of genetic origin and without symptoms, with total participation lasting at least the assessment day.

CONDITIONS

Brief Title

Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic Volunteers

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Volunteers aged between 18 and 65 years
  • Able to walk without assistance
  • Able to stand up from a chair with armrests at least 3 times within 30 seconds
  • Able to climb an inclined plane independently or with assistance to access the movement analysis room
  • Provide informed consent to participate
  • Member of or beneficiary of a social security system
  • For volunteers with neuromuscular disease: confirmed genetic diagnosis of Spinal Muscular Atrophy, Charcot-Marie-Tooth, Muscular Dystrophy, or Myotonic Dystrophy
  • Ability to walk for 2 minutes without assistance
Not Eligible

You will not qualify if you...

  • Individuals under guardianship, curatorship, or legal protection
  • Pregnant or breastfeeding women
  • Non-ambulatory individuals
  • Individuals with epilepsy
  • Skin conditions preventing placement of VICON motion sensors
  • Asymptomatic volunteers with unstable respiratory or cardiac problems
  • Asymptomatic volunteers with neurological, musculoskeletal, or psychiatric problems
  • Volunteers with recent trauma or serious falls within the last 6 months
  • Volunteers who have fallen more than twice in the past year and at least once in the past three months
  • Use of assistive devices such as rigid knee braces or walkers
  • Unstable cardiomyopathy
  • Individuals awaiting diagnosis
  • Inability to comply with study protocol requirements
  • Medical or social conditions that could interfere with the study, as judged by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Gait Analysis

Duration - 1 day

Participants walk with shoes in a gait analysis room wearing VICON markers while being filmed by two smartphones to compare marker-based and markerless gait analysis.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Centre d'Exploration et d'Évaluation Neuromusculaire

Paris, France

Actively Recruiting

Loading map...

Research Team

P

Pauline SANTMARTY, MsC

R

Romain FEIGEAN, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

Similar Trials

A Phase 2 Double-Blinded, Randomized, Placebo-Controlled Stu...

Spinal Muscular Atrophy (SMA)

Actively Recruiting

17 locations

A Two-part Multicenter Study: a Randomized, Double-blind, Pl...

Limb Girdle Muscular Dystrophy

Actively Recruiting

6 locations

A Phase 1/Phase 2 Open-label Single Arm Study With Dose Esca...

Myotonic Dystrophy

Actively Recruiting

9 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here