Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07321977

Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic Volunteers

Led by Institut de Myologie, France · Updated on 2026-01-07

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

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AI-Summary

What this Trial Is About

In recent years, knowledge of neuromuscular diseases has advanced considerably, and new therapeutic avenues are beginning to emerge. The proliferation of clinical trials has created a need to identify biomarkers that are both sensitive to changes and specific to the disease. Current gait tests only consider the time factor and not the evolution of the patient's biomechanics, which may prove insufficient for patients whose symptoms generally progress slowly. Quantifying gait parameters in neuromuscular patients therefore appears necessary. This is why we propose to study markerless gait analysis in this population, which would allow for simple and effective monitoring of kinematic parameters without resorting to complex equipment incompatible with routine clinical practice.

CONDITIONS

Official Title

Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic Volunteers

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Volunteers aged 18 to 65 years
  • Able to walk independently
  • Provided informed consent to participate
  • Member or beneficiary of a social security system
  • For neuromuscular disease volunteers: confirmed genetic diagnosis of a listed neuromuscular disease
  • Ability to walk for 2 minutes without assistance
  • Ability to stand up from a chair with armrests at least 3 times in 30 seconds
  • Ability to climb an inclined plane independently or with assistance to access the analysis room
Not Eligible

You will not qualify if you...

  • Individuals under guardianship, curatorship, or legal protection
  • Pregnant or breastfeeding women
  • Non-ambulatory individuals
  • People with epilepsy
  • Skin conditions preventing placement of motion sensors
  • For asymptomatic volunteers: unstable respiratory or cardiac problems
  • Neurological, musculoskeletal, or psychiatric problems in asymptomatic volunteers
  • For neuromuscular disease volunteers: recent trauma or serious falls within 6 months
  • More than two falls in the past year and at least one fall in the past three months
  • Use of assistive devices like rigid knee braces or walkers
  • Unstable cardiomyopathy
  • Awaiting diagnosis of neuromuscular disease
  • Inability to comply with study protocol
  • Medical or social conditions interfering with study participation

AI-Screening

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Trial Site Locations

Total: 1 location

1

Centre d'Exploration et d'Évaluation Neuromusculaire

Paris, France

Actively Recruiting

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Research Team

P

Pauline SANTMARTY, MsC

CONTACT

R

Romain FEIGEAN, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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