Actively Recruiting

Phase Not Applicable
Age: 0 - 60Years
All Genders
Healthy Volunteers
NCT07178288

Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)

Led by The Hashemite University · Updated on 2025-11-18

38

Participants Needed

1

Research Sites

15 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus. Participants complete brief questionnaires (basic demographics without names, a tennis-elbow symptom form, and a physical-activity form) and then have their pressure-pain threshold (PPT) tested with a handheld device that slowly increases pressure on standard spots near the elbow and wrist; they say when it first becomes painful. To test the body's built-in anti-pain system (conditioned pain modulation, CPM), one hand is placed in ice water (the cold-pressor task) and PPT is measured again at set times (before, during, and after the cold stimulus) to see how much pain sensitivity changes and how long that change lasts. Both PPT reliability and CPM after effect are measured in this study. The study findings may help improve future assessment and treatment of musculoskeletal pain conditions.

CONDITIONS

Official Title

Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)

Who Can Participate

Age: 0 - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with tennis elbow confirmed by the primary investigator
  • Unilateral elbow pain lasting more than 6 weeks
  • Pain reproduced by at least two tests: palpation of lateral epicondyle, wrist extensor isometric test, middle finger extension, passive wrist extensor stretch, resisted hand grip, or upper limb neurodynamic test (radial nerve bias)
  • Adults aged 18 to 65 years without pain for at least 3 months (healthy group)
Not Eligible

You will not qualify if you...

  • History of chronic pain conditions such as fibromyalgia, irritable bowel syndrome, temporomandibular dysfunction, or migraines
  • Neurological or sensory dysfunction, especially in upper limbs
  • History of chronic musculoskeletal pain including arthritis or chronic low back pain
  • Contraindications to cold application like Reynaud's disease or diabetes
  • Current or long-term use of pain medication or antidepressants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Hashemite University, Department of Physical Therapy; Community Rehabilitation Center Clinics

Zarqa, Zarqa Governorate, Jordan, 13115

Actively Recruiting

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Research Team

A

Ahmad Muhsen, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE) | DecenTrialz