Actively Recruiting
Assessment of Lung Function After General Anesthesia Using Sevoflurane or Desflurane in Obese Patients Undergoing Bariatric Surgery
Led by Medical University of Gdansk · Updated on 2025-01-06
100
Participants Needed
1
Research Sites
64 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how different inhaled anesthetics affect lung function in obese patients undergoing bariatric surgery. The study focuses on assessing lung function before anesthesia induction and after awakening from general anesthesia. It is known that anesthesia can impair lung function, with inhalation anesthetics like sevoflurane potentially causing less reduction in lung function parameters compared to intravenous anesthetics. Participants will be randomly assigned to receive general anesthesia with either sevoflurane or desflurane. This comparison aims to understand the impact of these two inhalation anesthetics on lung function during and after bariatric surgery. During the study, researchers will continuously monitor heart rate, oxygen levels, carbon dioxide levels, anesthetic concentration, and brain activity throughout anesthesia. Lung function tests will be performed three months before surgery and then at 10 and 30 minutes after waking from anesthesia. These tests include measurements of forced vital capacity, expiratory flow rates, respiratory impedance, and related lung function parameters. The study will track these measures to evaluate changes related to the anesthetic used.
CONDITIONS
Official Title
Assessment of Pulmonary Function in Relation to the Anesthetic Used in Patients Undergoing Bariatric Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Obese patients qualified for bariatric surgery
You will not qualify if you...
- Patients with absolute contraindications to spirometry testing
- Patients with aneurysms of the aorta or cerebral arteries threatening to rupture or after recent vascular surgery
- Patients with increased intracranial pressure, recent intracranial bleeding, or recent cranial surgery
- Patients after acute conditions within 6 months prior to surgery such as stroke, myocardial infarction, unstable angina, or pneumothorax
- Patients with uncontrolled hypertension
- Patients after recent eye surgery or with a history of retinal detachment
- Patients with hemoptysis of unknown cause
- Patients unable to perform spirometry testing
AI-Screening
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Trial Site Locations
Total: 1 location
1
University Clinical Center
Gdansk, Poland
Actively Recruiting
Research Team
K
Karolina Obara, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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