Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05023265

Assessment of Quality of Life and Outcomes in Patients With Primary Renal Cell Carcinoma Treated With SBRT

Led by Sunnybrook Health Sciences Centre · Updated on 2026-04-28

70

Participants Needed

1

Research Sites

242 weeks

Total Duration

On this page

Sponsors

S

Sunnybrook Health Sciences Centre

Lead Sponsor

J

Juravinski Cancer Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a multicenter, single arm phase II study of stereotactic body radiation therapy (SBRT) for patients with medically inoperable primary renal cell carcinoma (RCC).

CONDITIONS

Official Title

Assessment of Quality of Life and Outcomes in Patients With Primary Renal Cell Carcinoma Treated With SBRT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 18 years old or older
  • Newly diagnosed RCC by biopsy or radiologic evidence of tumor growth over 6-12 months
  • Primary tumor larger than 3 cm or recurrent lesion after local therapy
  • Medically inoperable or patient refuses surgery after urologist assessment and multidisciplinary discussion
  • ECOG performance status 0 to 2
  • Able to provide written informed consent
  • Able to understand English or use a translator
Not Eligible

You will not qualify if you...

  • Primary tumor larger than 20 cm
  • Evidence of distant metastatic disease
  • Previous abdominal radiation near the kidney preventing SBRT
  • History of major radiosensitivity syndrome
  • Second invasive cancer within past 3 years (except non-melanoma skin cancer)
  • Currently pregnant or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sunnybrook Health Sciences

Toronto, Ontario, Canada

Actively Recruiting

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Research Team

C

Chris Zehr

CONTACT

K

Kerri Durrant

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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