Actively Recruiting
Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically
Led by Dartmouth-Hitchcock Medical Center · Updated on 2026-02-06
125
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
Sponsors
D
Dartmouth-Hitchcock Medical Center
Lead Sponsor
D
Dartmouth College
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary objective of this study is the evaluation of the efficacy of the tissue oxygen imager based on PpIX DF in differentiating benign skin growth from non-melanoma skin cancer (NMSC).
CONDITIONS
Official Title
Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 63 18 years of age
- Histologic proof of non-melanoma skin cancer
- Patients with different skin tones presenting with skin growth or lesions scheduled for resection
- Willingness and ability to understand and comply with study procedures
- Women of childbearing potential must have a negative pregnancy test within 7 days prior to study start
- Lesions must measure between 5 mm and 3 cm in diameter
You will not qualify if you...
- Patients younger than 18 years
- Adults unable to provide informed consent
- Known allergy to Ameluz
- Photosensitivity or photodermatoses or similar conditions
- Serious underlying medical conditions impairing treatment or compliance
- Known hypersensitivity to porphyrins or any component of Ameluz including soya bean phosphatidylcholine
- Females currently breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dartmouth Hitchcock
Lebanon, New Hampshire, United States, 03766
Actively Recruiting
Research Team
D
Dylan L Parker, MD
CONTACT
S
Staci Shaw
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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