Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT07087873

Assessment of Transcranial Alternating Current Stimulation's Clinical Efficacy in Treating Cognitive Impairment of Idiopathic Inflammatory Demyelinating Diseases

Led by Xuanwu Hospital, Beijing · Updated on 2025-07-28

128

Participants Needed

1

Research Sites

126 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to explore the imaging and electrophysiological characteristics of idiopathic inflammatory demyelinating diseases (IIDDs), and their correlation with clinical manifestations. It also evaluates the effectiveness of transcranial electrical stimulation in alleviating clinical symptoms of IIDDs patients, and analyzes the key factors affecting the treatment efficacy. By uncovering the overall and individual characteristics of IIDDs, this study seeks to enhance therapeutic outcomes through personalized neuromodulation programs. The findings will provide a basis for applying non-invasive brain stimulation (NIBS) in IIDDs treatment and offer new ideas for future personalized medicine approaches.

CONDITIONS

Official Title

Assessment of Transcranial Alternating Current Stimulation's Clinical Efficacy in Treating Cognitive Impairment of Idiopathic Inflammatory Demyelinating Diseases

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 60 years old
  • Diagnosed with neuromyelitis optica spectrum disease, multiple sclerosis, or other inflammatory demyelinating diseases of the central nervous system meeting diagnostic criteria
  • Medications have been stable for at least three months
Not Eligible

You will not qualify if you...

  • Disease recurrence recorded in the past 3 months
  • Presence of pacemaker or metal implant in the body
  • Impaired skin integrity where electrodes would be placed
  • Prior organic brain diseases such as epilepsy, hydrocephalus, central nervous system tumors, brain injury, or intracranial infection
  • Severe or unstable organic diseases including heart, liver, kidney, or other organ dysfunction
  • Pregnancy, lactation, or planning pregnancy in the near future
  • Poor compliance with study requirements
  • Any other condition deemed unsuitable by the investigator for study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100053

Actively Recruiting

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Research Team

H

huang huijin, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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