Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
FEMALE
NCT05761275

Assessment of Women's Sexual Quality of Life After Benign Adnexal Surgery Using vNOTES Approach

Led by Jean Dubuisson · Updated on 2025-03-27

62

Participants Needed

1

Research Sites

169 weeks

Total Duration

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AI-Summary

What this Trial Is About

Transvaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is a recent innovation in minimally invasive surgery which has already proven its non-inferiority to conventional abdominal laparoscopy (CAL) for hysterectomy in terms of efficiency and safety. However, the investigators note a lack of medical literature and no specific randomized controlled trial (RCT) assessing women's sexual function after vNOTES for benign adnexal surgery. The aim of this RCT is to confirm the non-inferiority of the vNOTES approach for benign adnexal pathology compared to CAL on women's sexual function. Secondary outcomes will evaluate vNOTES's efficiency, morbidity and postoperative complications compared to CAL for benign adnexal surgery. The relationship between adnexal mass morcellation/aspiration and the quality of the histological analysis on surgical specimens will also be evaluated as secondary outcome.

CONDITIONS

Official Title

Assessment of Women's Sexual Quality of Life After Benign Adnexal Surgery Using vNOTES Approach

Who Can Participate

Age: 18Years - 70Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged from 18 to 70 years
  • Ability to understand the study and provide oral and written consent
  • Engaged in heterosexual vaginal intercourse within four weeks before joining the study
Not Eligible

You will not qualify if you...

  • History of rectal surgery
  • Suspected rectovaginal or retrocervical endometriosis
  • History of brachytherapy or pelvic radiation
  • Suspected malignancy
  • History of severe pelvic inflammatory disease
  • Active infection of the lower genital tract
  • Pregnancy
  • Not fluent in French or English
  • Under legal guardianship or lacking judgment capacity

AI-Screening

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Trial Site Locations

Total: 1 location

1

Geneva University Hospital

Geneva, Switzerland, 1205

Actively Recruiting

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Research Team

E

Eloïse Krull

CONTACT

J

Jean Dubuisson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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