Actively Recruiting
Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDS
Led by Bicetre Hospital · Updated on 2025-02-11
100
Participants Needed
1
Research Sites
186 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Intubated patients with the acute respiratory distress syndrome (ARDS) are usually treated with protective ventilation limiting plateau pressure below 30 centimeter of water (cmH2O) and, if possible, a driving pressure under 15 cmH2O. However, these airway pressures might not reflect the actual pressure applied to the lung. Transpulmonary pressure is the difference between airway pressure and pleural pressure, the latter is estimated by the esophageal pressure, and so it better reflects the ventilatory induced lung injury (VILI). One of the consequences of the VILI is a increase of pulmonary edema and it could be estimated by the extravascular lung water, obtained by trans-pulmonary thermodilution. So it could exist a link between the driving trans-pulmonary pressure and the extravascular lung water.
CONDITIONS
Official Title
Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of acute respiratory distress syndrome (ARDS)
- Monitoring with a transpulmonary thermodilution device
- Esophageal pressure monitoring
You will not qualify if you...
- Under legal protection measures
- Pregnancy
- Contraindications for esophageal catheter such as esophageal varicose or severe coagulopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical Intensive Care Unit, Bicêtre Hospital
Le Kremlin-Bicêtre, France
Actively Recruiting
Research Team
T
Tài Pham, MD, PhD.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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