Actively Recruiting
Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-28
1000
Participants Needed
4
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are examining how exercise affects cancer-specific outcomes and other health measures in adult cancer survivors. This retrospective study uses observational data to mimic a clinical trial, aiming to understand the impact of exercise after cancer treatment. The study is sponsored by Memorial Sloan Kettering Cancer Center and focuses on patients who have completed primary cancer treatment and are under surveillance for recurrence or remission. Participants are divided into groups based on their exercise habits following treatment. One group follows usual care, while the other group reports engaging in exercise after completing active therapy for their primary cancer. The study uses data from exercise surveys completed as part of the Cancer Survivorship Program at Memorial Sloan Kettering, assessing exercise levels at baseline and historically to classify non-exercising and exercising patients. During the study, participants' exercise status is tracked through surveys, and clinical outcomes such as distant disease-free survival over five years are measured. Researchers will review medical records to confirm no recurrence or metastasis before baseline assessment. Data collection includes patient-reported exercise frequency and intensity as well as clinical monitoring carried out during routine cancer survivorship care. The study spans data collected between 2011 and 2023, with ongoing follow-up to evaluate long-term outcomes.
CONDITIONS
Brief Title
Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years of age or older with a history of primary invasive cancer under surveillance at Memorial Sloan Kettering Cancer Center (MSK)
- Completion of a baseline exercise survey as part of the MSK Cancer Survivorship Program
- Non-exercising status (less than 10 metabolic equivalent-hours per week) reported 9-15 months prior to baseline in the historical exercise survey
- No evidence of recurrent or metastatic disease in the 15 months before the baseline exercise assessment
- Completion of all definitive primary adjuvant therapy at least 3 months before the historical exercise survey
- Participation in the MSK Cancer Survivorship Program under surveillance
- For observational emulation: adult cancer survivors under MSK surveillance between 2011 and 2023
- Self-reported exercise status via MSK Cancer Survivorship Program surveys
- Documented history of absolute contraindications to moderate exercise (congestive heart failure, valvular disease, chronic pulmonary disease, renal failure) prior to baseline
- Adjuvant hormonal therapy permitted at any time
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 5 years
Participants are monitored over time to observe exercise habits, patient-reported outcomes, and clinical events after completion of active cancer treatment.
Trial Site Locations
Total: 4 locations
1
City of Hope Cancer Center (Data Analysis Only)
Duarte, California, United States, 91010
Not Yet Recruiting
2
University of California, Los Angeles (Data or Specimen Analysis Only)
Los Angeles, California, United States, 90095-1781
Not Yet Recruiting
3
Weill Cornell Medical College (Data or Specimen Analysis Only)
New York, New York, United States, 10021
Not Yet Recruiting
4
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
Research Team
J
Jessica Scott, PhD
C
Chaya Moskowitz, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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