Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07030686

Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-28

1000

Participants Needed

4

Research Sites

365 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This protocol is a retrospective study using observational data to conduct a target trial emulation to examine the association of exercise on cancer specific endpoints and other clinical outcomes in cancer survivors.

CONDITIONS

Official Title

Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older with a history of primary invasive cancer under surveillance at Memorial Sloan Kettering Cancer Center (MSK)
  • Completion of an exercise survey at baseline as part of MSK Cancer Survivorship Program
  • Completion of a historical exercise survey 9-15 months prior reporting non-exercising status (less than 10 MET-hours per week)
  • No evidence of recurrent or metastatic disease in the 15 months before baseline exercise assessment
  • Completion of all definitive primary adjuvant therapy at least 3 months before the historical exercise survey; adjuvant hormonal therapy allowed anytime
  • Undergoing surveillance in the MSK Cancer Survivorship Program
  • Adult cancer survivors under surveillance at MSK between 2011 and 2023
  • Self-reported non-exercising status (less than 5 MET-hours per week) 9-15 months before baseline assessment
  • Documented history of absolute contraindications to moderate-intensity exercise assessed by specific medical conditions (congestive heart failure, valvular disease, chronic pulmonary disease, or renal failure)
  • No evidence of recurrent or metastatic disease by radiological or pathological records in the 15 months before baseline
  • Completion of all definitive primary adjuvant therapy at least 3 months before the historical exercise survey; adjuvant endocrine therapy permitted
Not Eligible

You will not qualify if you...

  • Patients who completed an additional exercise survey between the historical survey and baseline
  • Evidence of recurrent or metastatic disease in the 15 months before baseline exercise assessment
  • Presence of absolute contraindications to moderate-intensity exercise such as congestive heart failure, valvular disease, chronic pulmonary disease, or renal failure before baseline exercise assessment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

City of Hope Cancer Center (Data Analysis Only)

Duarte, California, United States, 91010

Not Yet Recruiting

2

University of California, Los Angeles (Data or Specimen Analysis Only)

Los Angeles, California, United States, 90095-1781

Not Yet Recruiting

3

Weill Cornell Medical College (Data or Specimen Analysis Only)

New York, New York, United States, 10021

Not Yet Recruiting

4

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States, 10065

Actively Recruiting

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Research Team

J

Jessica Scott, PhD

CONTACT

C

Chaya Moskowitz, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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