Actively Recruiting
Association Between GalectiN-3 and POSt-operative AtrIal Fibrillation After Coronary Artery BypaSs Graft
Led by University of Sao Paulo General Hospital · Updated on 2025-01-10
90
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG). The main question\[s\] it aims to answer are: * Is Galectin-3 an accurate biomarker to predict higher risk of developing post-operative atrial fibrillation? * Are high levels of Galectin-3 associated to other post-operative complications and major adverse cardiovascular events? Participants will be enrolled during pre-operative evaluation and a peripheral blood sample collection will be performed in the 24h before CABG. Participants will then be followed for a period of 12 months (daily during hospitalization and 3 appointments after hospital discharge) to determine whether patients with higher levels of Galectin-3 will have worse outcomes.
CONDITIONS
Official Title
Association Between GalectiN-3 and POSt-operative AtrIal Fibrillation After Coronary Artery BypaSs Graft
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing coronary artery bypass graft surgery
You will not qualify if you...
- Unable to sign informed consent
- Renal dysfunction with estimated glomerular filtration rate less than 30 ml/min/1.73m² or on dialysis
- Moderate to severe left ventricular dysfunction (ejection fraction < 40%)
- History of atrial fibrillation
- Pregnancy
- Undergoing valve surgery along with CABG
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Instituto do Coração - Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo
São Paulo, São Paulo, Brazil, 05403000
Actively Recruiting
Research Team
E
Eduardo Lima
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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