Pilot Study on Using Near-Infrared Spectroscopy to Monitor Kidney Oxygen Levels During Lung Transplant Surgery and Predict Early Kidney Failure

What this Trial Is About

Researchers are investigating the relationship between kidney oxygen levels during lung transplant surgery and the risk of kidney failure shortly after the operation. This observational study focuses on acute kidney injury, which affects more than half of lung transplant patients and sometimes requires kidney support treatments. The study aims to see if near-infrared spectroscopy NIRS, a non-invasive method measuring kidney tissue oxygen, can predict early postoperative kidney failure by monitoring kidney hypoxia during surgery. Participants undergoing lung transplantation will have their kidney oxygen saturation measured using NIRS throughout the surgery. This technique has been used in heart surgeries but not extensively studied in lung transplants. The researchers will calculate a renal hypoxia index combining the depth and duration of low kidney oxygen levels during the operation to evaluate its predictive value for kidney failure. During the study, patients will be monitored closely for kidney function and complications for five days after surgery. Outcomes such as early acute kidney failure, use of kidney support therapies, survival status, changes in kidney function tests, and lung graft health will be recorded. This monitoring will help determine if intraoperative kidney oxygen monitoring can guide prevention strategies and improve outcomes after lung transplantation.

Association Between Renal Regional Oxygen Saturation Measured by Near-InfraRed Spectroscopy and Postoperative Renal Failure After Lung Transplantation Surgery: A Pilot Study