Actively Recruiting

Age: 21Years - 70Years
All Genders
Healthy Volunteers
NCT04805320

Association of Periodontal Inflammation on Immune Response in Wound Healing

Led by University of Nebraska · Updated on 2025-12-10

25

Participants Needed

1

Research Sites

252 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.

CONDITIONS

Official Title

Association of Periodontal Inflammation on Immune Response in Wound Healing

Who Can Participate

Age: 21Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Need for extraction of a non-restorable posterior tooth (molar or premolar)
Not Eligible

You will not qualify if you...

  • Presence of systemic disease that affects inflammation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Nebraska, College of Dentistry

Lincoln, Nebraska, United States, 68583

Actively Recruiting

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Research Team

A

Amy C Killeen, DDS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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