Actively Recruiting

Age: 14Years - 75Years
All Genders
Healthy Volunteers
NCT05496582

The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma

Led by Shanghai University of Traditional Chinese Medicine · Updated on 2024-05-08

100

Participants Needed

2

Research Sites

213 weeks

Total Duration

On this page

Sponsors

S

Shanghai University of Traditional Chinese Medicine

Lead Sponsor

X

Xiangya Hospital of Central South University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.

CONDITIONS

Official Title

The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma

Who Can Participate

Age: 14Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Males or females, aged 14-75 years
  • Patients with a definite diagnosis of bronchial asthma
  • Diagnosis of asthma according to the Global Initiative for Asthma (GINA) with positive bronchodilator responsiveness test
  • Healthy volunteers without respiratory symptoms such as cough, wheezing, chest tightness, or dyspnea
  • Agree to all procedures by signing written informed consent
Not Eligible

You will not qualify if you...

  • Patients with chronic obstructive pulmonary disease or other airway disease
  • Presence of severe primary diseases such as hypertension, cancer, hyperthyroidism, bronchiectasia, cardiac insufficiency, or other conditions preventing participation or causing risk
  • Women known to be pregnant or breastfeeding
  • Unwillingness to participate
  • History of psychiatric or neurological disorders that impair normal functioning
  • Other conditions deemed inappropriate for participation by the researcher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Xiangya Hospital, Central South University

Changsha, Hunan, China, 410000

Actively Recruiting

2

Yueyang Hospital, Shanghai University of Traditional Chinese Medicine

Shanghai, Shanghai Municipality, China, 200030

Not Yet Recruiting

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Research Team

L

Lei-Miao Yin, MD

CONTACT

J

Jun-Tao Feng, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma | DecenTrialz