Actively Recruiting
Study of Urinary BDNF and NGF Levels Linked to Lower Urinary System Changes in Men Aged 50 to 80 With Benign Prostate Enlargement and Bladder Outlet Obstruction
Led by Marmara University · Updated on 2025-08-22
70
Participants Needed
1
Research Sites
21 weeks
Total Duration
AI-Summary
What this Trial Is About
Benign Prostatic Hyperplasia BPH is a common condition in older men characterized by enlargement of the prostate, leading to lower urinary tract symptoms LUTS such as frequent urination, urgency, nocturia, difficulty urinating, and feeling of incomplete bladder emptying. This study investigates the levels of nerve growth factor NGF and brain-derived neurotrophic factor BDNF in urine samples to understand their role in bladder outlet obstruction caused by BPH and the related changes in the bladder. Researchers aim to compare these levels before and after surgical procedures to relieve obstruction, as well as with control patients without obstruction.
CONDITIONS
Brief Title
Association of Urine BDNF and NGF With Lower Urinary System Parameters
Research Team
H
Haydar Kamil ÇAM, Prof. Dr.
K
Kader Ada Doğan, MD
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