Actively Recruiting
Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Stroke
Led by Parc de Salut Mar · Updated on 2024-08-07
100
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cryptogenic stroke (CS) causes about 30% of admissions to a stroke unit. Silent paroxysmal atrial fibrillation (PAF) is believed to be the underlying cause of a significant proportion of patients. The use of implantable cardiac monitors (ICM) early after the CS has demonstrated benefits in the diagnostic yield, but the indication for ICM in the current guidelines remains unclear. Atrial contraction strain (ACS) evaluated by cardiac ultrasound could be of help to select the patients more prone to suffer from silent PAF. The purpose of this investigation is to conduct a randomized prospective unicentric study to evaluate the usefulness of ICM for early detection of silent PAF episodes in patients with CS. Clinical and ultrasound predictors of PAF occurrence (ACS) will be studied in order to define patients needing a closer follow-up.
CONDITIONS
Official Title
Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute ischemic stroke or transient ischemic attack (TIA) from January 2022 to July 2023
- Age between 50 and 89 years
- Undetermined stroke origin at hospital admission by SSS-TOAST criteria
- No major structural heart disease by cardiac ultrasound
- No atrial fibrillation during 48-hour ECG monitoring
- No major anomalies in supra-aortic trunk ultrasound
You will not qualify if you...
- History of hemorrhagic stroke
- Prior atrial fibrillation or atrial flutter
- Permanent contraindication or indication for oral anticoagulation for other reasons
- Major surgery or cardiac events within the last month
- Severe cardiac abnormalities
- Life expectancy less than 1 year or severe stroke (modified Rankin Scale greater than 4)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital del Mar
Barcelona, Spain, 08003
Actively Recruiting
Research Team
E
Ermengol Valles Gras, PhD
CONTACT
A
Ana Beatriz Garcia Duran, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
4
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