Actively Recruiting
Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study
Led by Tulane University · Updated on 2026-03-04
60
Participants Needed
3
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF).
CONDITIONS
Official Title
Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 75 years
- Diagnosed with mild, moderate, or severe obstructive sleep apnea confirmed by polysomnography
- No previous diagnosis of atrial fibrillation for groups A, B, and C
- History of atrial fibrillation allowed for groups D and E with mild or severe OSA
- Control group with no previous diagnosis of OSA or atrial fibrillation
- Patients with AF and OSA who already underwent MRI may be included in groups D and E
You will not qualify if you...
- History of chronic heart failure with left ventricular ejection fraction less than 50%, atrial fibrillation, myocardial infarction, or valvular disease
- Prior cardiac or chest surgery
- Severe chronic obstructive pulmonary disease, severe asthma, pulmonary hypertension, or central sleep apnea
- Contraindications to DE-MRI such as allergy to gadolinium, presence of pacemakers, defibrillators, or other MRI-incompatible devices
- Glomerular filtration rate below 30 ml/min
- Pregnancy
- Inability to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
East Jefferson General Hospital
New Orleans, Louisiana, United States, 70006
Actively Recruiting
2
University Medical Center
New Orleans, Louisiana, United States, 70112
Actively Recruiting
3
Tulane Doctors - Speciality Care - Napoleon
New Orleans, Louisiana, United States, 70115
Actively Recruiting
Research Team
C
Christian Massad, MD
CONTACT
K
Kunal Sameer, MD, MHA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
6
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