MRI Evaluation of Atrial Scar Tissue Using Gadolinium in Patients Aged 13 and Older with Repaired Congenital Heart Disease

What this Trial Is About

This research focuses on patients aged 13 and older with congenital heart disease who have undergone surgical repair and may develop atrial arrhythmias such as intra-atrial reentrant tachycardia and atrial fibrillation. The study aims to better understand how well scar tissue in the hearts atria can be seen using cardiac MRI with a contrast agent called gadolinium. Researchers want to learn how these MRI findings relate to measurements taken during procedures in the electrophysiology laboratory. Participants will have cardiac MRI scans as part of their usual medical care, involving the use of gadolinium contrast to visualize scar tissue in the hearts atria. The study will analyze 3D late gadolinium enhancement images to quantify atrial fibrosis and compare these findings with voltage maps obtained during electrophysiology procedures. This imaging technique is being evaluated for its reproducibility and potential to provide insight into heart tissue changes in patients with repaired congenital heart disease. During the study, participants will undergo cardiac MRI scans and may have electrophysiology laboratory evaluations as part of their routine care. Researchers will measure total atrial fibrosis using 3D late gadolinium enhancement MRI over one year and compare it with voltage mapping results over two years. They will also track occurrences of sustained atrial arrhythmias lasting more than 30 seconds over five years using ECG and monitoring methods. The study is observational and focuses on collecting detailed imaging and clinical data to better understand heart scarring in this population.

Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease