Actively Recruiting
Assessment of Left And Right Atrial Strain in Septic Shock
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-01-16
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
C
Centre Hospitalier Universitaire, Amiens
Lead Sponsor
H
Henri Mondor University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Septic shock is a life-threatening condition with high mortality rates. Researchers are studying how left and right atrial strain (LAS and RAS) measurements, obtained through speckle tracking echocardiography, can help evaluate heart function in these patients. This observational study focuses on comparing two echocardiographic software programs, ECHOPAC and UWS, to understand differences in their LAS and RAS measurements, and to test a new AutoStrain technology for measurement reproducibility among observers. The study uses retrospective data from adult patients treated for septic shock who had transthoracic echocardiography (TTE) as part of their care. It compares variations in several atrial strain measurements between the two software tools, including analyses from different heart views and measurement modes. The study also assesses how consistent the measurements are when performed manually or with AutoStrain, across different observers. Participants are adults over 18 treated for septic shock with available echocardiographic data. Researchers review existing echocardiograms and collect various atrial strain measurements over one year. They evaluate measurement differences, reproducibility, and the effectiveness of AutoStrain technology. This non-interventional study involves no new treatments or procedures and will contribute to improving heart function assessment in critically ill patients.
CONDITIONS
Brief Title
Atrial Strain in Septic Shock
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Adult patients admitted to critical care for septic shock as defined by SEPSIS-3
- Transthoracic echocardiography (TTE) performed as part of medical management
- No objection to use of data for research
You will not qualify if you...
- Pregnancy
- Moderate to severe valvular regurgitation or stenosis greater than grade 2
- Ventricular or supraventricular tachyarrhythmia with heart rate over 140 bpm at time of TTE
- Poor echogenicity preventing left atrial strain measurement
- Mechanical circulatory support
- Pacemaker dependence
- Patients under legal guardianship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 1 year
Participants undergo transthoracic echocardiography (TTE) as part of their medical management to assess atrial strain.
Multiple assessments during the year
Duration - 1 year
Participants are monitored for variations in atrial strain measurements and related outcomes over one year.
Trial Site Locations
Total: 1 location
1
CHRU Amiens
Salouël, France, 80480
Actively Recruiting
Research Team
C
Christophe Beyls, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here