What is this study trying to find out about septic shock?

This study aims to compare different echocardiographic software methods for measuring left and right atrial strain in patients with septic shock. Researchers want to understand how these measurements vary between software and assess the reproducibility of a new AutoStrain technology. The goal is to improve heart function evaluation in critically ill patients.

Who may be eligible for this septic shock clinical trial?

Adults aged 18 years or older admitted to critical care with septic shock who have undergone transthoracic echocardiography may be eligible. Both males and females can participate, but pregnancy and certain heart conditions may exclude participation. Please review eligibility criteria for more details.

Is there any cost to participate in this septic shock clinical trial?

Study-related care, including data analysis and all trial assessments, is provided at no cost. Personal travel or other expenses are not covered and may vary. Participants should plan accordingly.

Actively Recruiting

Age: 18Years +

All Genders

ID06832436

Evaluation of Left and Right Atrial Strain Measurements in Adults with Septic Shock Using Echocardiographic Software

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-01-16

Participants Needed

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Septic shock is a life-threatening condition with high mortality rates. Researchers are studying how left and right atrial strain LAS and RAS measurements, obtained through speckle tracking echocardiography, can help evaluate heart function in these patients. This observational study focuses on comparing two echocardiographic software programs, ECHOPAC and UWS, to understand differences in their LAS and RAS measurements, and to test a new AutoStrain technology for measurement reproducibility among observers. The study uses retrospective data from adult patients treated for septic shock who had transthoracic echocardiography TTE as part of their care. It compares variations in several atrial strain measurements between the two software tools, including analyses from different heart views and measurement modes. The study also assesses how consistent the measurements are when performed manually or with AutoStrain, across different observers. Participants are adults over 18 treated for septic shock with available echocardiographic data. Researchers review existing echocardiograms and collect various atrial strain measurements over one year. They evaluate measurement differences, reproducibility, and the effectiveness of AutoStrain technology. This non-interventional study involves no new treatments or procedures and will contribute to improving heart function assessment in critically ill patients.

CONDITIONS

Brief Title

Atrial Strain in Septic Shock

Who Can Participate

Age: 18Years +

All Genders

Eligibility Criteria

You may qualify if you...

Age over 18 years
Adult patients admitted to critical care for septic shock as defined by SEPSIS-3
Transthoracic echocardiography (TTE) performed as part of medical management
No objection to use of data for research

You will not qualify if you...

Pregnancy
Moderate to severe valvular regurgitation or stenosis greater than grade 2
Ventricular or supraventricular tachyarrhythmia with heart rate over 140 bpm at time of TTE
Poor echogenicity preventing left atrial strain measurement
Mechanical circulatory support
Pacemaker dependence
Patients under legal guardianship

Research Team

Christophe Beyls, MD

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