Actively Recruiting
Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-12
44
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
URC-CIC Paris Descartes Necker Cochin
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim is to determine whether vestibular deficits are present in OI, then to establish whether a correlation exists between genetic type, severity of OI and audiovestibular phenotype. OI patients aged 12 to 20 years will undergo an audiometric, immittance, and vestibular assessment. When hearing loss is conductive or mixed or in cases where vestibular deficits are identified, a CT scan without injection will be performed. In case of sensorineural hearing loss or abnormal CT results, an MRI will be performed.
CONDITIONS
Official Title
Audio-vestibular Evaluation of Children and Young Adults With Osteogenesis Imperfecta
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients between the ages of 12-20 years at the time of inclusion
- Diagnosis of Osteogenesis Imperfecta of any type
- Currently followed by a physician at the CRMR OI
- Information and non-opposition of major patients, holders of parental authority and minor patients to participate in the study
You will not qualify if you...
- Patients with hearing loss of alternate origin e.g. Cochlear nerve deficiency, atresia, etc.
- Neurological or developmental deficits limiting participation
- Cervico-occipital instability e.g. Chiari's malformation
- Limitations in mobility of the spine e.g. scoliosis, spinal fractural fusion
- Ophthalmologic pathologies e.g. strabism or severe refraction disorder
- Patients under AME (State Medical Aid)
- Protected adult patients, adults unable to express their consent, pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hôpital Necker-Enfants Malades
Paris, France, 75015
Actively Recruiting
Research Team
N
Natalie Loundon, MD, PhD
CONTACT
H
Hélène Morel
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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