Actively Recruiting

Age: 18Years +
All Genders
NCT05415631

Augmented Bladder Tumor Detection Using Real Time Based Artificial Intelligence

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2022-07-15

500

Participants Needed

1

Research Sites

363 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Today the standard for the diagnosis and monitoring of bladder tumors is bladder endoscopy. The performance of this exam is not perfect. With this work, based on artificial intelligence, the investigators wish to combine endoscopy with a complementary diagnostic tool in order to improve patient care. The main objective will be to reduce diagnostic errors / wanderings in patients treated or followed for bladder tumors, by imposing a new standard of diagnostic bladder mapping (high PPV and VPN, high precision)(primary purpose diagnostic). The secondary objective will be to homogenize and systematize the descriptive part of the lesions, and to use AI to better characterize tumor aggressiveness. The final objective being to validate a new precision tool (diagnostic companion) essential for developing and standardizing the therapeutic management of bladder tumors (correcting inter-observer heterogeneity). In this project, video frame will be first extracted from our dataset of cystoscopy videos hosted in in the Next Cloud Recherche. Selected medical image will be segmented and analyzed using our pre-trained CNN model with a feature detection algorithm to obtain features. Data will be analyzed on both patient and lesion levels. The study will assess the Bladder-PAD accuracy on the detection of bladder tumors, and its ability to predict tumor risk of recurrence and progression.

CONDITIONS

Official Title

Augmented Bladder Tumor Detection Using Real Time Based Artificial Intelligence

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Unifocal primary or recurrent suspected bladder cancer with tumor size less than or equal to 3 cm
  • Multifocal primary or recurrent suspected bladder cancer with 5 or fewer lesions each less than or equal to 3 cm
Not Eligible

You will not qualify if you...

  • More than 5 tumors or any tumor larger than 3 cm
  • Suspected muscle-invasive bladder cancer (cT2 or higher) by computed tomography or cystoscopy
  • Evidence of distant metastases by computed tomography or magnetic resonance imaging
  • Gross hematuria
  • Bacillus Calmette-Guerin (BCG) treatment or chemotherapy within 3 months before inclusion, except a single course of chemotherapy immediately after TUR
  • Patients who do not consent to use of their data for research

AI-Screening

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Trial Site Locations

Total: 1 location

1

Amiens University Hospital

Amiens, France, 80054

Actively Recruiting

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Research Team

F

Fabien SAINT, Pr

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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